Publikationen
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Maas-Bauer K, Stell AV, Yan KL, de Vega E, Vinnakota JM, Unger S, Núñez N, Norona J, Talvard-Balland N, Koßmann S, Schwan C, Miething C, Martens US, Shoumariyeh K, Nestor RP, Duquesne S, Hanke K, Rackiewicz M, Hu Z, El Khawanky N, Taromi S, Andrlova H, Faraidun H, Walter S, Pfeifer D, Follo M, Waldschmidt J, Melchinger W, Rassner M, Wehr C, Schmitt-Graeff A, Halbach S, Liao J, Häcker G, Brummer T, Dengjel J, Andrieux G, Grosse R, Tugues S, Blazar BR, Becher B, Boerries M, Zeiser R (2024) ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nat Commun, 15, 446, 1-15
Abstract
Papatheodorou P, Minton NP, Aktories K, Barth H (2024) An Updated View on the Cellular Uptake and Mode-of-Action of Clostridioides difficile Toxins. Adv Exp Med Biol, 1435, 219-47
Abstract
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Aktories K (2023) Clostridioides difficile infection drives neuronal inflammation. Nature, 622, 465-7
Abstract
Aktories K (2023) From signal transduction to protein toxins-a narrative review about milestones on the research route of C. difficile toxins. Naunyn Schmiedebergs Arch Pharmacol, 396, 173-90
Abstract
Behren S, Schorlemer M, Schmidt G, Aktories K, Westerlind U (2023) Antibodies Directed Against GalNAc- and GlcNAc-O-Tyrosine Posttranslational Modifications - a New Tool for Glycoproteomic Detection. Chemistry, 29, e202300392, 1-13
Abstract
Francois L, Boskovic P, Knerr J, He W, Sigismondo G, Schwan C, More TH, Schlotter M, Conway ME, Krijgsveld J, Hiller K, Grosse R, Lichter P, Radlwimmer B (2023) BCAT1 redox function maintains mitotic fidelity. Cell Rep, 42, 112217, Erratum for 41, 111524
Abstract
Frank D, Moussie JC, Ulferts S, Lorenzen L, Schwan C, Grosse R (2023) Vesicle-Associated Actin Assembly by Formins Promotes TGFβ-Induced ANGPTL4 Trafficking, Secretion and Cell Invasion. Adv Sci (Weinh), 10, e2204896, 1-9
Abstract
Jakob D, Schmoor C, Reuten R, Frevert ML, Dannehl D, Jansen L, Hermann S, Jungmann P, Hartkopf AD, Juhasz-Böss I, Taran FA (2023) Characteristics, Treatment Patterns and Survival of International Federation of Gynecology and Obstetrics Stage IV Epithelial Ovarian Cancer – A Population-Based Study. Cancers (Basel), 15, 5676, 1-13
Abstract
Just A, Mallmann RT, Grossmann S, Sleman F, Klugbauer N (2023) Two-pore channel protein TPC1 is a determining factor for the adaptation of proximal tubular phosphate handling. Acta Physiol (Oxf), 237, e13914, 1-17
Abstract
Knerr J, Werner R, Schwan C, Wang H, Gebhardt P, Grötsch H, Caliebe A, Spielmann M, Holterhus PM, Grosse R, Hornig NC (2023) Formin-mediated nuclear actin at androgen receptors promotes transcription. Nature, 617, 616-22
Abstract
Lan C, Kim J, Ulferts S, Aprile-Garcia F, Weyrauch S, Anandamurugan A, Grosse R, Sawarkar R, Reinhardt A, Hugel T (2023) Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation. Nat Commun, 14, 4831, 1-8
Abstract
Lorenzen L, Frank D, Schwan C, Grosse R (2023) Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation. Biomolecules, 13, 548, 1-14
Abstract
Meier M, Gupta M, Akgül S, McDougall M, Imhof T, Nikodemus D, Reuten R, Moya-Torres A, To V, Ferens F, Heide F, Padilla-Meier GP, Kukura P, Huang W, Gerisch B, Mörgelin M, Poole K, Antebi A, Koch M, Stetefeld J (2023) The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation. Nat Commun, 14, 1226, 1-18
Abstract
Ojasalu K, Lieber S, Sokol AM, Nist A, Stiewe T, Bullwinkel I, Finkernagel F, Reinartz S, Müller-Brüsselbach S, Grosse R, Graumann J, Müller R (2023) The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis. Theranostics, 13, 1921-48
Abstract
Palumbieri MD, Merigliano C, González-Acosta D, Kuster D, Krietsch J, Stoy H, von Känel T, Ulferts S, Welter B, Frey J, Doerdelmann C, Sanchi A, Grosse R, Chiolo I, Lopes M (2023) Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity. Nat Commun, 14, 7819, 1-15
Abstract
Rafaeva M, Jensen ARD, Horton ER, Zornhagen KW, Strøbech JE, Fleischhauer L, Mayorca-Guiliani AE, Nielsen SR, Grønseth DS, Kuś F, Schoof EM, Arnes L, Koch M, Clausen-Schaumann H, Izzi V, Reuten R, Erler JT (2023) Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression. Front Immunol, 14, 1154528, 1-12
Abstract
Su C, Rodriguez-Franco M, Lace B, Nebel N, Hernandez-Reyes C, Liang P, Schulze E, Mymrikov EV, Gross NM, Knerr J, Wang H, Siukstaite L, Keller J, Libourel C, Fischer AAM, Gabor KE, Mark E, Popp C, Hunte C, Weber W, Wendler P, Stanislas T, Delaux PM, Einsle O, Grosse R, Römer W, Ott T (2023) Stabilization of membrane topologies by proteinaceous remorin scaffolds. Nat Commun, 14, 323, 1-16
Abstract
Wardas B, Schneider JG, Klugbauer N, Flockerzi V, Beck A (2023) Englerin A inhibits T-type CaV channels at low-micromolar concentrations. Mol Pharmacol, 104, 144-53
Abstract
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Aigal S, Omidvar R, Stober K, Ziegelbauer J, Eierhoff T, Schampera JN, Römer W, Schwan C (2022) Septin barriers protect mammalian host cells against Pseudomonas aeruginosa invasion. Cell Rep, 41, 111510, 1-17
Abstract
Aktories K (2022) Another surprise in receptor binding of C. difficile toxins. Innovation (Camb), 3, 100261, 1-2
Abstract
Aktories K (2022) Treatment of ovarian cancer with modified anthrax toxin. Proc Natl Acad Sci U S A, 119 (32), e2210179119, 1-3
Abstract
Cobb AM, De Silva SA, Hayward R, Sek K, Ulferts S, Grosse R, Shanahan CM (2022) Filamentous nuclear actin regulation of PML NBs during the DNA damage response is deregulated by prelamin A. Cell Death Dis, 13, 1042, 1-12
Abstract
Francois L, Boskovic P, Knerr J, He W, Sigismondo G, Schwan C, More TH, Schlotter M, Krijgsveld J, Hiller K, Grosse R, Lichter P, Radlwimmer B (2022) BCAT1 redox function maintains mitotic fidelity. Cell Rep, 41, 111524, 1-25
Abstract
Kaleta T, Kern L, Hong SL, Hölzer M, Kochs G, Beer J, Schnepf D, Schwemmle M, Bollen N, Kolb P, Huber M, Ulferts S, Weigang S, Dudas G, Wittig A, Jaki L, Padane A, Lagare A, Salou M, Ozer EA, Nnaemeka N, Odoom JK, Rutayisire R, Benkahla A, Akoua-Koffi C, Ouedraogo AS, Simon-Lorière E, Enouf V, Kröger S, Calvignac-Spencer S, Baele G, Panning M, Fuchs J (2022) Antibody escape and global spread of SARS-CoV-2 lineage A.27. Nat Commun, 13, 1152, 1-13
Abstract
Reuten R, Mayorca-Guiliani AE, Erler JT (2022) Matritecture: Mapping the extracellular matrix architecture during health and disease. Matrix Biol Plus, 14, 100102, 1-6
Abstract
Schoellkopf J, Mueller T, Hippchen L, Mueller T, Reuten R, Backofen R, Orth J, Schmidt G (2022) Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein 1 (LRP1) as crucial cellular receptor. PLoS Pathog, 18, e1010781, 1-16
Abstract
Schwan C, Lang AE, Schlosser A, Fujita-Becker S, AlHaj A, Schröder RR, Faix J, Aktories K, Mannherz HG (2022) Inhibition of Arp2/3 Complex after ADP-Ribosylation of Arp2 by Binary Clostridioides Toxins. Cells, 11, 3661, 1-21
Abstract
Simpson M, Frisbee A, Kumar P, Schwan C, Aktories K, Petri WA (2022) Clostridioides difficile binary toxin (CDT) is recognized by the TLR2/6 heterodimer to induce an NF-κB response. J Infect Dis, 225, 1296-300
Abstract
Zähringer S, Rumpf T, Melesina J, Lang AE, Aktories K, Sippl W, Jung M, Wagner GK (2022) Defined stereoisomers of 2"-amino NAD+ and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase. Bioorg Med Chem, 68, 116875, 1-11
Abstract
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Grossmann S, Mallmann RT, Klugbauer N (2021) Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways. Cells, 10, 1807, 1-13
Abstract
Kowarschik S, Schöllkopf J, Müller T, Tian S, Knerr J, Bakker H, Rein S, Dong M, Weber S, Grosse R, Schmidt G (2021) Yersinia pseudotuberculosis cytotoxic necrotizing factor interacts with glycosaminoglycans. FASEB J, 35, e21647, 1-16
Abstract
Li Y, Schön C, Chen CC, Yang Z, Liegl R, Murenu E, Schworm B, Klugbauer N, Grimm C, Wahl-Schott C, Michalakis S, Biel M (2021) TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration. Life Sci Alliance, 4, e202101047, 1-13
Abstract
Liang P, Schmitz C, Lace B, Ditengou FA, Su C, Schulze E, Knerr J, Grosse R, Keller J, Libourel C, Delaux PM, Ott T (2021) Formin-mediated bridging of cell wall, plasma membrane, and cytoskeleton in symbiotic infections of Medicago truncatula. Curr Biol, 31, 2712-19
Abstract
Müller T, Grossmann S, Mallmann RT, Rommel C, Hein L, Klugbauer N (2021) Two-pore channels affect EGF receptor signaling by receptor trafficking and expression. iScience, 24, 1-30
Abstract
Ng'ang'a PN, Siukstaite L, Lang AE, Bakker H, Römer W, Aktories K, Schmidt G (2021) Involvement of N-glycans in binding of Photorhabdus luminescens Tc toxin. Cell Microbiol, 23, e13326, 1-16
Abstract
Papatheodorou P, Kindig S, Badilla-Lobo A, Fischer S, Durgun E, Thuraisingam T, Witte A, Song S, Aktories K, Chaves-Olarte E, Rodríguez C, Barth H (2021) The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB. Front Microbiol, 12, 784856, 1-10
Abstract
Probst S, Sagar, Tosic J, Schwan C, Grün D, Arnold SJ (2021) Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Development, 48, dev193789, 1-15
Abstract
Safaralizade M, Fuderer R, Grosse R, Zhao B (2021) Measuring nuclear calcium and actin assembly in living cells. J Biochem, 169, 287-94
Abstract
Szczęśniak P, Henke T, Fröhlich S, Plessmann U, Urlaub H, Leng L, Bucala R, Grosse R, Meinhardt A, Klug J (2021) Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independent of its receptor CD74/CD44. J Cell Sci, 134, 1-12
Abstract
Trefzer R, Elpeleg O, Gabrusskaya T, Stepensky P, Mor-Shaked H, Grosse R, Brandt DT (2021) Characterization of a L136P mutation in Formin-like 2 (FMNL2) from a patient with chronic inflammatory bowel disease. PLoS One, 16, e0252428, 1-17
Abstract
Ulferts S, Prajapati B, Grosse R, Vartiainen MK (2021) Emerging Properties and Functions of Actin and Actin Filaments Inside the Nucleus. Cold Spring Harb Perspect Biol, 13, 1-16
Abstract
Vannini E, Mori E, Tantillo E, Schmidt G, Caleo M, Costa M (2021) CTX-CNF1 Recombinant Protein Selectively Targets Glioma Cells In Vivo. Toxins (Basel), 13, 194, 1-11
Abstract
Weigang S, Fuchs J, Zimmer G, Schnepf D, Kern L, Beer J, Luxenburger H, Ankerhold J, Falcone V, Kemming J, Hofmann M, Thimme R, Neumann-Haefelin C, Ulferts S, Grosse R, Hornuss D, Tanriver Y, Rieg S, Wagner D, Huzly D, Schwemmle M, Panning M, Kochs G (2021) Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants. Nat Commun, 12, 6405, 1-12
Abstract
Zhao B, Grosse R (2021) Optogenetic Control of Myocardin-Related Transcription Factor A Subcellular Localization and Transcriptional Activity Steers Membrane Blebbing and Invasive Cancer Cell Motility. Adv Biol (Weinh), 5, 2000208, 1-10
Abstract
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Aktories K (2020) Semaphorins or Frizzled -it is the receptor that direct the action of clostridial glucosylating toxins. Signal Transduct Target Ther, 5, 206, 1-2
Abstract
Antoni C, Quentin D, Lang AE, Aktories K, Gatsogiannis C, Raunser S (2020) Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. PLoS Pathog, 16, e1008530, 1-19
Abstract
Arlt E, Fraticelli M, Tsvilovskyy V, Nadolni W, Breit A, O'Neill TJ, Resenberger S, Wennemuth G, Wahl-Schott C, Biel M, Grimm C, Freichel M, Gudermann T, Klugbauer N, Boekhoff I, Zierler S (2020) TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity. Proc Natl Acad Sci U S A, 117, 18068-78
Abstract
Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Hüttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu J, Bouhaddou S, Mathy CJP, Gaulton A, Manners EJ, Félix E, Shi Y, Goff M, Lim JK, McBride T, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, De Wit E, Leach AR, Kortemme T, Shoichet B, Ott M, Saez-Rodriguez J, tenOever BR, Mullins RD, Fischer ER, Kochs G, Grosse R, García-Sastre A, Vignuzzi M, Johnson JR, Shokat KM, Swaney DL, Beltrao P, Krogan NJ (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell, 182, 685-712
Abstract
Fischer S, Ückert AK, Landenberger M, Papatheodorou P, Hoffmann-Richter C, Mittler AK, Ziener U, Hägele M, Schwan C, Müller M, Kleger A, Benz R, Popoff MR, Aktories K, Barth H (2020) Human Peptide α-defensin-1 Interferes With Clostridioides Difficile Toxins TcdA, TcdB, and CDT. FASEB J, 34, 6244-61
Abstract
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR 3rd, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH Jr, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D; QCRG Structural Biology Consortium, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL; Zoonomia Consortium, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, García-Sastre A, Rassen JA, Grosse R, Rosenberg OS, Verba KA, Basler CF, Vignuzzi M, Peden AA, Beltrao P, Krogan NJ (2020) Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science, 370, eabe9403, 1-25
Abstract
Korbmacher M, Fischer S, Landenberger M, Papatheodorou P, Aktories K, Barth H (2020) Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT. Front Pharmacol, 11, 1204, 1-10
Abstract
Krippner S, Winkelmeier J, Knerr J, Brandt DT, Virant D, Schwan C, Endesfelder U, Grosse R (2020) Postmitotic expansion of cell nuclei requires nuclear actin filament bundling by α-actinin 4. EMBO Rep, 21, e50758, 1-11
Abstract
Lacinova L, Mallmann RT, Jurkovičová-Tarabová B, Klugbauer N (2020) Modulation of voltage-gated CaV2.2 Ca2+ channels by newly identified interaction partners. Channels (Austin), 14, 380-92
Abstract
Mallmann RT, Klugbauer N (2020) Genetic Inactivation of Two-Pore Channel 1 Impairs Spatial Learning and Memory. Behav Genet, 50, 401-10
Abstract
Okuno T, Li WY, Hatano Y, Takasu A, Sakamoto Y, Yamamoto M, Ikeda Z, Shindo T, Plessner M, Morita K, Matsumoto K, Yamagata K, Grosse R, Miyamoto K (2020) Zygotic Nuclear F-Actin Safeguards Embryonic Development. Cell Rep, 31, 107824, 1-23
Abstract
Ost GS, Wirth C, Bogdanović X, Kao WC, Schorch B, Aktories PJK, Papatheodorou P, Schwan C, Schlosser A, Jank T, Hunte C, Aktories K (2020) Inverse Control of Rab Proteins by Yersinia ADP-ribosyltransferase and Glycosyltransferase Related to Clostridial Glucosylating Toxins. Sci Adv, 6, eaaz2094, 1-12
Abstract
Richter L, Oberländer V, Schmidt G (2020) RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A. Sci Rep, 10, 12532, 1-11
Abstract
Schiavon, C. R., Zhang, T., Zhao, B., Moore, A. S., Wales, P., Andrade, L. R., Wu, M., Sung, T. C., Dayn, Y., Feng, J. W., Quintero, O. A., Shadel, G. S., Grosse, R., & Manor, U (2020) Actin chromobody imaging reveals sub-organellar actin dynamics. Nature methods, 17, 917–21
Abstract
Schwan C, Grosse R (2020) A tight grip on differentiation: Nuclear constriction by microtubules regulates hematopoietic stem cells. EMBO J, e107086, 1-3
Abstract
Taskinen ME, Närvä E, Conway JRW, Hinojosa LS, Lilla S, Mai A, De Franceschi N, Elo LL, Grosse R, Zanivan S, Norman JC, Ivaska J (2020) MASTL Promotes Cell Contractility and Motility Through Kinase-Independent Signaling. J Cell Biol, 219, e201906204, 1-23
Abstract
Yamazaki S, Gerhold C, Yamamoto K, Ueno Y, Grosse R, Miyamoto K, Harata M (2020) The Actin-Family Protein Arp4 Is a Novel Suppressor for the Formation and Functions of Nuclear F-Actin. Cells, 9, 758, 1-14
Abstract
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Abdellatif MEA, Hipp L, Plessner M, Walther P, Knöll B (2019) Indirect visualization of endogenous nuclear actin by correlative light and electron microscopy (CLEM) using an actin-directed chromobody. Histochem Cell Biol, 152, 133-43
Abstract
Aktories K, Gierschik P, Heringdorf DMZ, Schmidt M, Schultz G, Wieland T (2019) cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology-tribute to Karl H. Jakobs. Naunyn Schmiedebergs Arch Pharmacol, 392, 887-911
Abstract
Almonacid M, Al Jord A, El-Hayek S, Othmani A, Coulpier F, Lemoine S, Miyamoto K, Grosse R, Klein C, Piolot T, Mailly P, Voituriez R, Genovesio A, Verlhac MH (2019) Active Fluctuations of the Nuclear Envelope Shape the Transcriptional Dynamics in Oocytes. Dev Cell, 51, 145-57
Abstract
Bogdanović X, Schneider S, Levanova N, Wirth C, Trillhaase C, Steinemann M, Hunte C, Aktories K, Jank T (2019) A cysteine protease-like domain enhances the cytotoxic effects of the Photorhabdus asymbiotica toxin PaTox. J Biol Chem, 294, 1035-44
Abstract
Brander S, Jank T, Hugel T (2019) AFM Imaging Suggests Receptor-Free Penetration of Lipid Bilayers by Toxins. Langmuir, 35, 365-71
Abstract
Caridi CP, Plessner M, Grosse R, Chiolo I (2019) Nuclear actin filaments in DNA repair dynamics. Nat Cell Biol, 21, 1068-77
Abstract
Chleilat E, Mallmann R, Spanagel R, Klugbauer N, Krieglstein K, Roussa E (2019) Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons. Front Cell Neurosci, 13, 427, 1-19
Abstract
Ebner JK, König GM, Kostenis E, Siegert P, Aktories K, Orth JH (2019) Activation of Gq signaling by Pasteurella multocida toxin inhibits the osteoblastogenic-like actions of Activin A in C2C12 myoblasts, a cell model of fibrodysplasia ossificans progressiva. Bone, 127, 592-601
Abstract
Levanova N, Mattheis C, Carson D, To KN, Jank T, Frankel G, Aktories K, Schroeder GN (2019) The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase. J Biol Chem, 294, 2862-79
Abstract
Levanova N, Steinemann M, Böhmer KE, Schneider S, Belyi Y, Schlosser A, Aktories K, Jank T (2019) Characterization of the glucosyltransferase activity of Legionella pneumophila effector SetA. Naunyn Schmiedebergs Arch Pharmacol, 392, 69-79
Abstract
López-Ureña D, Orozco-Aguilar J, Chaves-Madrigal Y, Ramírez-Mata A, Villalobos-Jimenez A, Ost S, Quesada-Gómez C, Rodríguez C, Papatheodorou P, Chaves-Olarte E (2019) Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors. Toxins (Basel). 11, 384, 1-15
Abstract
Mallmann RT, Moravcikova L, Ondacova K, Lacinova L, Klugbauer N (2019) Grina/TMBIM3 modulates voltage-gated Cav2.2 Ca2+ channels in a G-protein-like manner. Cell Calcium, 80, 71-8
Abstract
Mallmann R, Ondacova K, Moravcikova L, Jurkovicova-Tarabova B, Pavlovicova M, Moravcik R, Lichvarova L, Kominkova V, Klugbauer N, Lacinova L (2019) Four novel interaction partners demonstrate diverse modulatory effects on voltage-gated CaV2.2 Ca2+ channels. Pflugers Arch, 471, 861-74
Abstract
Müller CS, Bildl W, Klugbauer N, Haupt A, Fakler B, Schulte U (2019) High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis. J Vis Exp, 152, e60096, 1-10
Abstract
Ng Ang A PN, Ebner JK, Plessner M, Aktories K, Schmidt G (2019) Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine. Life Sci Alliance, 2, e20190048, 1-12
Abstract
Ost GS, Ng'ang'a PN, Lang A, Aktories K (2019) Photorhabdus luminescens Tc toxin is inhibited by the protease inhibitor MG132 and activated by protease cleavage resulting in increased binding to target cells. Cell Microbiol, 21, e12978, 1-12
Abstract
Papatheodorou P, Song S, López-Ureña D, Witte A, Marques F, Ost GS, Schorch B, Chaves-Olarte E, Aktories K (2019) Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway. FASEB J, 33, 4883-92
Abstract
Plessner M, Grosse R (2019) Dynamizing nuclear actin filaments. Curr Opin Cell Biol, 56, 1-6
Abstract
Plessner M, Knerr J, Grosse R (2019) Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression. iScience, 15, 274-81
Abstract
Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R (2019) Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment. Mol Oncol, 13, 185-201
Abstract
Schnell L, Felix I, Müller B, Sadi M, von Bank F, Papatheodorou P, Popoff MR, Aktories K, Waltenberger E, Benz R, Weichbrodt C, Fauler M, Frick M, Barth H (2019) Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication. FASEB J, 33, 5755-71
Abstract
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29 January 2024