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Postdoc in cardiovascular epigenetics
The Institute of Experimental and Clinical Pharmacology and Toxicology at the University of Freiburg invites applications for a Postdoctoral fellow (m/f/d) in cardiovascular epigenetics.
Our lab is interested in the interplay of transcription factors and epigenetic regulatory mechanisms in cardiovascular disease with focus on the mineralocorticoid receptor. We aim to develop new approaches for cell-selective pharmacological targeting.
We use state-of-the-art technology in molecular biology (RNAseq, single cell RNAseq, ATACseq, ChIPseq, Cut&Run;, RIME) with bioinformatics as well as cell culture techniques including iPS cells, flow cytometry, and transgenic mouse models. We provide a stimulating working atmosphere in an interdisciplinary group and seek excellent and highly motivated candidates to join our team. Our group is embedded in the DFG Collaborative Research Centre SFB 1425 “Heterocellular Nature of Cardiac Lesions” and provides opportunities for close interactions with other teams working on cardiac epigenetics, inflammation, or imaging.
Candidates should have an excellent degree in molecular medicine, molecular biology, pharmacology, pharmacy, biochemistry or other related fields and a strong scientific background. Experience in molecular and cellular biology techniques is required.
Please address your application including CV, certificates and letters of recommendation to: PD Dr. Achim Lother
Institute of Experimental und Clinical Pharmacology and Toxicology, University of Freiburg, achim.lother[at]uniklinik-freiburg.de.
The Preissl Lab has openings for both computational and wet lab candidates!
PhD students/Doktoranden and Postdocs:
We are looking for enthusiastic and creative PhD students and Postdocs to reveal gene regulatory mechanisms of cardiovascular diseases using cutting-edge single cell epigenomics, multiomics technologies and functional perturbation assays. For our studies we use clinical samples, mouse models, cell culture and stem cell differentiation models.
Qualifications:
• Master degree or PhD degree in any field with strong interest in gene regulation, epigenomics, functional genomics and high dimensional data analysis.
• Experience with analysis and/or generating epigenomic datasets (ATAC-seq, ChIP-seq, CUT&Tag;) and single cell genomics datasets (single cell RNA-seq, single cell ATAC-seq) are preferred, but not required.
• For wet lab candidates, experience with in vitro differentiation of cardiomyocytes or organoid culture is a plus.
• Candidates with experience in both wet and dry lab are highly encouraged to apply.
• Excellent communication and collaborative skills.
Interested candidates please send one pdf with following documents to sebastian.preissl[at]pharmakol.uni-freiburg.de:
1) Motivation letter including your research interests
2) CV
3) Contact information for two to three references
Medical students (medizinische Doktorarbeit), master and diploma students:
Students interested in thesis work please contact us about potential projects. Please send a statement of your research interest and a CV to: sebastian.preissl[at]pharmakol.uni-freiburg.de.
16. April 2024