Publikationen

2024 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, Gomez de Agüero M, Gagliani N, Flavell RA, Backes S, Kastenmüller W, Gasteiger G (2024) Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection. Immunity, 57, 124-40
Abstract

Wang S, Klein SO, Urban S, Staudt M, Barthes NPF, Willmann D, Bacher J, Sum M, Bauer H, Peng L, Rennar GA, Gratzke C, Schüle KM, Zhang L, Einsle O, Greschik H, MacLeod C, Thomson CG, Jung M, Metzger E, Schüle R (2024) Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity. Nat Commun, 15, 43, 1-12
Abstract

2023 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Bojti I, Przewosnik AS, Luxenburger H, Hofmann M, Neumann-Haefelin C, Esser JS, Siegel PM, Maier A, Kovacs SB, Kardos L, Csanádi Z, Rieder M, Duerschmied D, Lother A, Bode C, Szabó GT, Czuriga D (2023) Decreased level of serum NT-proCNP associates with disease severity in COVID-19. Respir Res, 24, 174, 1-12
Abstract

Gaulton KJ, Preissl S, Ren B (2023) Interpreting non-coding disease-associated human variants using single-cell epigenomics. Nat Rev Genet, 24, 516-34
Abstract

Guo M, Wikenheiser-Brokamp KA, Kitzmiller JA, Jiang C, Wang G, Wang A, Preissl S, Hou X, Buchanan J, Karolak JA, Miao Y, Frank DB, Zacharias WJ, Sun X, Xu Y, Gu M, Stankiewicz P, Kalinichenko VV, Wambach JA, Whitsett JA (2023) Single Cell Multiomics Identifies Cells and Genetic Networks Underlying Alveolar Capillary Dysplasia. Am J Respir Crit Care Med, 208, 709-25
Abstract

Koca D, Lother A (2023) Molecular pharmacology of mineralocorticoid receptor antagonists: The role of co-regulators. Steroids, 109291, 1-33
Abstract

Lother A, Kohl P (2023) The heterocellular heart: identities, interactions, and implications for cardiology. Basic Res Cardiol, 118, 30, 1-22
Abstract

Mamazhakypov A, Lother A (2023) Therapeutic targeting of mineralocorticoid receptors in pulmonary hypertension: Insights from basic research. Front Cardiovasc Med, 10, 1118516, 1-12
Abstract

Nielsen CM, Barrett JR, Davis C, Fallon JK, Goh C, Michell AR, Griffin C, Kwok A, Loos C, Darko S, Laboune F, Tekman M, Diouf A, Miura K, Francica JR, Ransier A, Long CA, Silk SE, Payne RO, Minassian AM, Lauffenburger DA, Seder RA, Douek DC, Alter G, Draper SJ (2023) Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01_B malaria vaccine. JCI Insight, 8, e163859, 1-19
Abstract

Preissl S, Gaulton KJ, Ren B (2023) Characterizing cis-regulatory elements using single-cell epigenomics. C Nat Rev Genet, 24, 21-43
Abstract

Raviram R, Raman A, Preissl S, Ning J, Wu S, Koga T, Zhang K, Brennan CW, Zhu C, Luebeck J, Van Deynze K, Han JY, Hou X, Ye Z, Mischel AK, Li YE, Fang R, Baback T, Mugford J, Han CZ, Glass CK, Barr CL, Mischel PS, Bafna V, Escoubet L, Ren B, Chen CC (2023) Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity. Proc Natl Acad Sci U S A, 120, e2210991120, 1-11
Abstract

Rieder M, Baldus N, Stallmann D, Jeserich M, Goller I, Wirth L, Pollmeier L, Hofmann M, Bode C, Busch HJ, Schmid B, Gauchel N, Scharf RE, Duerschmied D, Lother A, Krauel K (2023) Early SARS-CoV-2 infection: platelet-neutrophil complexes and platelet function. Res Pract Thromb Haemost, 7, 100025, 1-12
Abstract

Riedhammer KM, Nguyen TT, Koşukcu C, Calzada-Wack J, Li Y, Batzir NA, Saygılı S, Wimmers V, Kim GJ, Chrysanthou M, Bakey Z, Sofrin-Drucker E, Kraiger M, Sanz-Moreno A, Amarie OV, Rathkolb B, Klein-Rodewald T, Garrett L, Hölter SM, Seisenberger C, Haug S, Schlosser P, Marschall S, Wurst W, Fuchs H, Gailus-Durner V, Wuttke M, de Angelis MH, Ćomić J, Doğan ÖA, Özlük Y, Taşdemir M, Ağbaş A, Canpolat N, Orenstein N, Çalışkan S, Weber RG, Bergmann C, Jeanpierre C, Saunier S, Lim TY, Hildebrandt F, Alhaddad B, Basel-Salmon L, Borovitz Y, Wu K, Antony D, Matschkal J, Schaaf CW, Renders L, Schmaderer C, Rogg M, Schell C, Meitinger T, Heemann U, Köttgen A, Arnold SJ, Ozaltin F, Schmidts M, Hoefele J (2023) Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int, Epub ahead of print
Abstract

Sassu E, Tumlinson G, Stefanovska D, Fernández MC, Iaconianni P, Madl J, Brennan T, Koch M, Cameron BA, Preissl S, Ravens U, Schneider-Warme F, Kohl P, Zgierski-Johnston CM, Hortells L (2023) Age-related structural and functional changes of the intracardiac nervous system. J Mol Cell Cardiol, Epub ahead of print
Abstract

Schüle KM, Weckerle J, Probst S, Wehmeyer AE, Zissel L, Schröder CM, Tekman M, Kim GJ, Schlägl IM, Sagar, Arnold SJ (2023) Eomes restricts Brachyury functions at the onset of mouse gastrulation. Dev Cell, 58, 1627-42
Abstract

Thelen B, Schipperges V, Knörlein P, Hummel JF, Arnold F, Kupferschmid L, Klose CSN, Arnold SJ, Boerries M, Tanriver Y (2023) Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4⁺ T cells. Front Immunol, 14, 1058267, 1-13
Abstract

Wang G, Chiou J, Zeng C, Miller M, Matta I, Han JY, Kadakia N, Okino ML, Beebe E, Mallick M, Camunas-Soler J, Dos Santos T, Dai XQ, Ellis C, Hang Y, Kim SK, MacDonald PE, Kandeel FR, Preissl S, Gaulton KJ, Sander M (2023) Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes. Nat Genet, 55, 984-94
Abstract

Xie F, Armand EJ, Yao Z, Liu H, Bartlett A, Behrens MM, Li YE, Lucero JD, Luo C, Nery JR, Pinto-Duarte A, Poirion OB, Preissl S, Rivkin AC, Tasic B, Zeng H, Ren B, Ecker JR, Mukamel EA (2023) Robust enhancer-gene regulation identified by single-cell transcriptomes and epigenomes. Cell Genom, 3, 100342, 1-16
Abstract

Zu S, Li YE, Wang K, Armand EJ, Mamde S, Amaral ML, Wang Y, Chu A, Xie Y, Miller M, Xu J, Wang Z, Zhang K, Jia B, Hou X, Lin L, Yang Q, Lee S, Li B, Kuan S, Liu H, Zhou J, Pinto-Duarte A, Lucero J, Osteen J, Nunn M, Smith KA, Tasic B, Yao Z, Zeng H, Wang Z, Shang J, Behrens MM, Ecker JR, Wang A, Preissl S, Ren B (2023) Single-cell analysis of chromatin accessibility in the adult mouse brain. Nature, 24, 378-89
Abstract

2022 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Abed S, Reilly A, Arnold SJ, Feldheim DA (2022) Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells. Front Cell Neurosci, 16, 826590, 1-13
Abstract

Ankerhold J, Giese S, Kolb P, Maul-Pavicic A, Voll RE, Göppert N, Ciminski K, Kreutz C, Lother A, Salzer U, Bildl W, Welsink T, Morgenthaler NG, Grawitz AB, Emmerich F, Steinmann D, Huzly D, Schwemmle M, Hengel H, Falcone V (2022) Circulating multimeric immune complexes contribute to immunopathology in COVID-19. Nat Commun, 13, 5654, 1-15
Abstract

Antony D, Gulec Yilmaz E, Gezdirici A, Slagter L, Bakey Z, Bornaun H, Tanidir IC, Van Dinh T, Brunner HG, Walentek P, Arnold SJ, Backofen R, Schmidts M (2022) Spectrum of Genetic Variants in a Cohort of 37 Laterality Defect Cases. Front Genet, 13, 861236, 1-15
Abstract

Bauersachs J, Lother A (2022) Mineralocorticoid receptor activation and antagonism in cardiovascular disease: cellular and molecular mechanisms. Kidney Int Suppl, 12, 19-26
Abstract

Clarisse D, Deng L, de Bosscher K, Lother A (2022) Approaches towards tissue-selective pharmacology of the mineralocorticoid receptor. Br J Pharmacol, 179, 3235-49
Abstract

Galaxy Community (2022) The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update. Nucleic Acids Res, 50, W345–51, Erratum in 50, 8999
Abstract

Gauchel N, Rieder M, Krauel K, Goller I, Jeserich M, Salzer U, Venhoff AC, Baldus N, Pollmeier L, Wirth L, Kern W, Rieg S, Busch HJ, Hofmann M, Bode C, Duerschmied D, Lother A, Heger LA (2022) Complement system component dysregulation is a distinctive feature of COVID-19 disease: a prospective and comparative analysis of patients admitted to the emergency department for suspected COVID-19 disease. J Thromb Thrombolysis, 53, 788-97
Abstract

Lother A, Jaisser F, Wenzel UO (2022) Emerging fields for therapeutic targeting of the aldosterone-mineralocorticoid receptor signaling pathway. Br J Pharmacol, 179, 3099-102
Abstract

Luo C, Liu H, Xie F, Armand EJ, Siletti K, Bakken TE, Fang R, Doyle WI, Stuart T, Hodge RD, Hu L, Wang BA, Zhang Z, Preissl S, Lee DS, Zhou J, Niu SY, Castanon R, Bartlett A, Rivkin A, Wang X, Lucero J, Nery JR, Davis DA, Mash DC, Satija R, Dixon JR, Linnarsson S, Lein E, Behrens MM, Ren B, Mukamel EA, Ecker JR (2022) Single nucleus multi-omics identifies human cortical cell regulatory genome diversity. Cell Genom, 2, 100106, 1-63
Abstract

Mamazhakypov A, Hein L, Lother A (2022) Mineralocorticoid receptors in pulmonary hypertension and right heart failure: From molecular biology to therapeutic targeting. Pharmacol Ther, 231
Abstract

Ngo V, Fleischmann BK, Jung M, Hein L, Lother A (2022) Histone Deacetylase 6 Inhibitor JS28 Prevents Pathological Gene Expression in Cardiac Myocytes. J Am Heart Assoc, 11, e025857, 1-13
Abstract

Nührenberg TG, Stöckle J, Marini F, Zurek M, Grüning BA, Benes V, Hein L, Neumann FJ, Stratz C, Cederqvist M, Hochholzer W (2022) Impact of high platelet turnover on the platelet transcriptome: Results from platelet RNA-sequencing in patients with sepsis. PLoS One, 17, e0260222, 1-20
Abstract

Simon-Chica A, Fernández MC, Wülfers EM, Lother A, Hilgendorf I, Seemann G, Ravens U, Kohl P, Schneider-Warme F (2022) Novel insights into the electrophysiology of murine cardiac macrophages: relevance of voltage-gated potassium channels. Cardiovasc Res, 118, 798-813
Abstract

Supady A, Zahn T, Rieder M, Benk C, Lother A, Bode C, Wengenmayer T, Staudacher D, Kellum JA, Duerschmied D (2022) Effect of Cytokine Adsorption on Survival and Circulatory Stabilization in Patients Receiving Extracorporeal Cardiopulmonary Resuscitation. ASAIO J, 68, 64-72
Abstract

Wehmeyer AE, Schüle KM, Conrad A, Schröder CM, Probst S, Arnold SJ (2022) Chimeric 3D gastruloids - a versatile tool for studies of mammalian peri-gastrulation development. Development, 149, dev200812, 1-8
Abstract

Zhang Y, Amaral ML, Zhu C, Grieco SF, Hou X, Lin L, Buchanan J, Tong L, Preissl S, Xu X, Ren B (2022) Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain. Cell Res, 32, 1008-21
Abstract

2021 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Biever P, Staudacher DL, Sommer MJ, Triebel H, Neukamm MA, Bode C, Supady A, Lother A (2021) Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID-19. Pharmacol Res Perspect, 9, 00743, 1-4
Abstract

Govindasamy N, Long H, Jeong HW, Raman R, Özcifci B, Probst S, Arnold SJ, Riehemann K, Ranga A, Adams RH, Trappmann B, Bedzhov I (2021) 3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels. Dev Cell, 56, 3276-87
Abstract

Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler O, Duerschmied D, Lother A, Rieg S, Gawaz M, Mueller KAL, Scheer C, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Floeel A, Lovreglio P, Stufano A, Marschalek R, Thiele T (2021) Anti-Platelet Factor 4 Antibodies Causing VITT do not Cross-React with SARS-CoV-2 Spike Protein. Blood, 138, 1269-77
Abstract

Hesse M, Bednarz R, Carls E, Becker C, Bondareva O, Lother A, Geisen C, Dreßen M, Krane M, Roell W, Hein L, Fleischmann BK, Gilsbach R (2021) Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes. J Mol Cell Cardiol, 152, 95-104
Abstract

El Khawanky N, Hughes A, Yu W, Myburgh R, Matschulla T, Taromi S, Aumann K, Clarson J, Vinnakota JM, Shoumariyeh K, Miething C, Lopez AF, Brown MP, Duyster J, Hein L, Manz MG, Hughes TP, White DL, Yong ASM, Zeiser R (2021) Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia. Nat Commun, 12, 6436, 1-20
Abstract

Kimura K, Ooms A, Graf-Riesen K, Kuppusamy M, Unger A, Schuld J, Daerr J, Lother A, Geisen C, Hein L, Takahashi S, Li G, Röll W, Bloch W, van der Ven PFM, Linke WA, Wu SM, Huesgen PF, Höhfeld J, Fürst DO, Fleischmann BK, Hesse M (2021) Overexpression of human BAG3^P209L in mice causes restrictive cardiomyopathy. Nat Commun, 12, 3575, 1-17
Abstract

Kowalski J, Deng L, Suennen C, Koca D, Meral D, Bode C, Hein L, Lother A (2021) Eplerenone Improves Pulmonary Vascular Remodeling and Hypertension by Inhibition of the Mineralocorticoid Receptor in Endothelial Cells. Hypertension, 78, 456-65
Abstract

Krane M, Dreßen M, Santamaria G, My I, Schneider CM, Dorn T, Laue S, Mastantuono E, Berutti R, Rawat H, Gilsbach R, Schneider P, Lahm H, Schwarz S, Doppler SA, Paige S, Puluca N, Doll S, Neb I, Brade T, Zhang Z, Abou-Ajram C, Northoff B, Holdt LM, Sudhop S, Sahara M, Goedel A, Dendorfer A, Tjong FVY, Rijlaarsdam ME, Cleuziou J, Lang N, Kupatt C, Bezzina C, Lange R, Bowles NE, Mann M, Gelb BD, Crotti L, Hein L, Meitinger T, Wu S, Sinnecker D, Gruber PJ, Laugwitz KL, Moretti A (2021) Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome. Circulation, 144, 1409-28
Abstract

Lother A, Bode C, Hein L (2021) Letter by Lother et al Regarding Article, "Finerenone and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Type 2 Diabetes". Circulation, 144, e201
Abstract

Lother A, Bondareva O, Saadatmand AR, Pollmeier L, Härdtner C, Hilgendorf I, Weichenhan D, Eckstein V, Plass C, Bode C, Backs J, Hein L, Gilsbach R (2021) Diabetes changes gene expression but not DNA methylation in cardiac cells. J Mol Cell Cardiol, 151, 74-87
Abstract

Probst S, Sagar, Tosic J, Schwan C, Grün D, Arnold SJ (2021) Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Development, 48, dev193789, 1-15
Abstract

Rieder M, Bode C, Duerschmied D, Lother A (2021) Response to: How important is the assessment of soluble ACE-2 in COVID-19? Am J Hypertens, 34, 298
Abstract

Rieder M, Duerschmied D, Zahn T, Lang C, Benk C, Lother A, Biever P, Bode C, Wengenmayer T, Staudacher D, Supady A (2021) Cytokine Adsorption in Severe Acute Respiratory Failure Requiring Veno-Venous Extracorporeal Membrane Oxygenation. ASAIO J, 67, 332-8
Abstract

Rieder M, Wirth L, Pollmeier L, Jeserich M, Goller I, Baldus N, Schmid B, Busch HJ, Hofmann M, Kern W, Bode C, Duerschmied D, Lother A (2021) Serum ACE-2, angiotensin II, and aldosterone levels are unchanged in patients with COVID-19. Am J Hypertens, 34, 278-81
Abstract

Rieder M, Wirth L, Pollmeier L, Jeserich M, Goller I, Baldus N, Schmid B, Busch HJ, Hofmann M, Thimme R, Rieg S, Kern W, Bode C, Duerschmied D, Lother A (2021) Serum protein profiling reveals a specific upregulation of the immunomodulatory protein progranulin in COVID-19. J Infect Dis, 223, 775-84
Abstract

Rieder M, Zahn T, Benk C, Lother A, Bode C, Staudacher D, Duerschmied D, Supady A (2021) Cytokine adsorption in a patient with severe coronavirus disease 2019 related acute respiratory distress syndrome requiring extracorporeal membrane oxygenation therapy: A case report. Artif Organs, 45, 191-94
Abstract

Roessner PM, Llaó Cid L, Lupar E, Roider T, Bordas M, Schifflers C, Arseni L, Gaupel AC, Kilpert F, Krötschel M, Arnold SJ, Sellner L, Colomer D, Stilgenbauer S, Dietrich S, Lichter P, Izcue A, Seiffert M (2021) EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4⁺ T cells in chronic lymphocytic leukemia. Leukemia, 35, 2311-24
Abstract

Weinstein B, da Silva AR, Kouzoukas DE, Bose T, Kim GJ, Correa PA, Pondugula S, Lee Y, Kim J, Carpenter DO (2021) Precision Mapping of COVID-19 Vulnerable Locales by Epidemiological and Socioeconomic Risk Factors, Developed Using South Korean Data. Int J Environ Res Public Health, 18, 604, 1-14
Abstract

Yim YY, McDonald WH, Betke KM, Kaya A, Hyde K, Erreger K, Gilsbach R, Hein L, Hamm HE (2021) Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α_2a-adrenergic receptors. Sci Signal, 14, eabc4970, 1-10
Abstract

2020 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Dannewitz Prosseda S, Ali MK, Spiekerkoetter E (2020) Novel Advances in Modifying BMPR2 Signaling in PAH. Genes (Basel), 12, 8, 1-10
Abstract

Deng L, Pollmeier L, Zhou Q, Bergemann S, Bode C, Hein L, Lother A (2020) Gene expression in immortalized versus primary isolated cardiac endothelial cells. Sci Rep, 10, 2241, 1-9
Abstract

Fixemer J, Hummel JF, Arnold F, Klose CSN, Hofherr A, Weissert K, Kögl T, Köttgen M, Arnold SJ, Aichele P, Tanriver Y (2020) Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells. PLoS Pathog, 16, e1008870, 1-27
Abstract

Hille L, Lenz M, Vlachos A, Grüning B, Hein L, Neumann FJ, Nührenberg TG, Trenk D (2020) Ultrastructural, Transcriptional and Functional Differences Between Human Reticulated and Non-Reticulated Platelets. J Thromb Haemost, 18, 2034-46
Abstract

Hoelscher SC, Stich T, Diehm A, Lahm H, Dreßen M, Zhang Z, Neb I, Aherrahrou Z, Erdmann J, Schunkert H, Santamaria G, Cuda G, Gilsbach R, Hein L, Lange R, Hassel D, Krane M, Doppler SA (2020) miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations. Int J Mol Sci, 21, 1158, 1-23
Abstract

Hummel JF, Zeis P, Ebert K, Fixemer J, Konrad P, Schachtrup C, Arnold SJ, Grün D, Tanriver Y (2020) Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1^- T-bet⁺ intraepithelial lymphocyte precursors. Mucosal Immunol, 13, 257-70
Abstract

Lang CN, Sommer MJ, Neukamm MA, Staudacher DL, Supady A, Bode C, Duerschmied D, Lother A (2020) Use of the CytoSorb adsorption device in MDMA intoxication: a first-in-man application and in vitro study. Intensive Care Med Exp, 8, 21, 1-8
Abstract

Lother A (2020) Mineralocorticoid Receptors: Master Regulators of Extracellular Matrix Remodeling. Circ Res, 127, 354-6
Abstract

Lother A, Kaier K, Ahrens I, Bothe W, Wolf D, Zehender M, Bode C, von Zur Mühlen C, Stachon P (2020) Bleeding Complications Drive In-Hospital Mortality of Patients with Atrial Fibrillation after Transcatheter Aortic Valve Replacement. Thromb Haemost, 1120, 1580-6
Abstract

Nelson BR, Hodge RD, Daza RA, Tripathi PP, Arnold SJ, Millen KJ, Hevner RF (2020) Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches. Elife, 9, e53777, 1-30
Abstract

Perez RE, Basu A, Nabit BP, Harris NA, Folkes OM, Patel S, Gilsbach R, Hein L, Winder DG (2020) α_2A-adrenergic heteroreceptors are required for stress-induced reinstatement of cocaine conditioned place preference. Neuropsychopharmacology, 45, 1473-81
Abstract

Popovitchenko T, Park Y, Page NF, Luo X, Krsnik Z, Liu Y, Salamon I, Stephenson JD, Kraushar ML, Volk NL, Patel SM, Wijeratne HRS, Li D, Suthar KS, Wach A, Sun M, Arnold SJ, Akamatsu W, Okano H, Paillard L, Zhang H, Buyske S, Kostovic I, De Rubeis S, Hart RP, Rasin MR (2020) Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development. Nat Commun, 11, 1674, 1-21
Abstract

Poveda-Huertes D, Matic S, Marada A, Habernig L, Licheva M, Myketin L, Gilsbach R, Tosal-Castano S, Papinski D, Mulica P, Kretz O, Kücükköse C, Taskin AA, Hein L, Kraft C, Büttner S, Meisinger C, Vögtle FN (2020) An Early mtUPR: Redistribution of the Nuclear Transcription Factor Rox1 to Mitochondria Protects against Intramitochondrial Proteotoxic Aggregates. Mol Cell, 77, 180-8
Abstract

Rieder M, Goller I, Jeserich M, Baldus N, Pollmeier L, Wirth L, Supady A, Bode C, Busch HJ, Schmid B, Duerschmied D, Gauchel N, Lother A (2020) Rate of venous thromboembolism in a prospective all-comers cohort with COVID-19. J Thromb Thrombolysis, 50, 558-66
Abstract

Rommel C, Hein L (2020) An Early mtUPR: Four Dimensions of the Cardiac Myocyte Epigenome: from Fetal to Adult Heart. Curr Cardiol Rep, 22, 26, 1-9
Abstract

Supady A, Duerschmied D, Bode C, Rieder M, Lother A (2020) Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19. Crit Care, 24, 514
Abstract

Tosic J, Kim GJ, Pavlovic M, Schröder CM, Mersiowsky SL, Barg M, Hofherr A, Probst S, Köttgen M, Hein L, Arnold SJ (2020) Author Correction: Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state. Nat Cell Biol, 22, 135. Erratum for: Nat Cell Biol, 21, 1518-31
Abstract

Yim YY, Betke KM, McDonald WH, Gilsbach R, Chen Y, Hyde K, Wang Q, Hein L, Hamm HE (2020) Author Correction: The in vivo specificity of synaptic Gβ and Gγ subunits to the α_2a adrenergic receptor at CNS synapses. Sci Rep, 10, 2966. Erratum for: Sci Rep, 9, 1718, 1-12
Abstract

2019 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Llorca A, Ciceri G, Beattie R, Wong FK, Diana G, Serafeimidou-Pouliou E, Fernández-Otero M, Streicher C, Arnold SJ, Meyer M, Hippenmeyer S, Maravall M, Marin O (2019) A stochastic framework of neurogenesis underlies the assembly of neocortical cytoarchitecture. Elife, 8, e51381, 1-27
Abstract

Lother A, Benk C, Staudacher DL, Supady A, Bode C, Wengenmayer T, Duerschmied D (2019) Cytokine Adsorption in Critically Ill Patients Requiring ECMO Support. Front Cardiovasc Med, 6, 71, 1-6
Abstract

Lother A, Deng L, Huck M, Fürst D, Kowalski J, Esser JS, Moser M, Bode C, Hein L (2019) Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis. J Endocrinol, 240, 15–26
Abstract

Rehman AU, Najafi M, Kambouris M, Al-Gazali L, Makrythanasis P, Rad A, Maroofian R, Rajab A, Stark Z, Hunter JV, Bakey Z, Tokita MJ, He W, Vetrini F, Petersen A, Santoni FA, Hamamy H, Wu K, Al-Jasmi F, Helmstädter M, Arnold SJ, Xia F, Richmond C, Liu P, Karimiani EG, Karami Madani G, Lunke S, El-Shanti H, Eng CM, Antonarakis SE, Hertecant J, Walkiewicz M, Yang Y, Schmidts M (2019) Biallelic loss of function variants in PPP1R21 cause a neurodevelopmental syndrome with impaired endocytic function. Hum Mutat, 40, 267-80
Abstract

Sheikh BN, Bondareva O, Guhathakurta S, Tsang TH, Sikora K, Aizarani N, Sagar, Holz H, Grün D, Hein L, Akhtar A (2019) Systematic Identification of Cell-Cell Communication Networks in the Developing Brain. iScience, 21, 273-87
Abstract

Tosic J, Kim GJ, Pavlovic M, Schröder CM, Mersiowsky SL, Barg M, Hofherr A, Probst S, Köttgen M, Hein L, Arnold SJ (2019) Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state. Nat Cell Biol, 21, 1518-31
Abstract

Yim YY, Betke KM, McDonald WH, Gilsbach R, Chen Y, Hyde K, Wang Q, Hein L, Hamm H (2019) The in vivo specificity of synaptic Gβ and Gγ subunits to the α_2a adrenergic receptor at CNS synapses. Sci Rep, 9, 1718, 1-12
Abstract

2018 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Abe P, Wüst HM, Arnold SJ, van de Pavert SA, Stumm R (2018) CXCL12-mediated feedback from granule neurons regulates generation and positioning of new neurons in the dentate gyrus. Glia, 66, 1566-76
Abstract

Deutsch MA, Doppler SA, Li X, Lahm H, Santamaria G, Cuda G, Eichhorn S, Ratschiller T, Dzilic E, Dreßen M, Eckart A, Stark K, Massberg S, Bartels A, Rischpler C, Gilsbach R, Hein L, Fleischmann BK, Wu SM, Lange R, Krane M (2018) Reactivation of the Nkx2.5 cardiac enhancer after myocardial infarction does not presage myogenesis. Cardiovasc Res, 114, 1098-114
Abstract

Gilsbach R, Schwaderer M, Preissl S, Grüning BA, Kranzhöfer D, Schneider P, Nührenberg TG, Mulero-Navarro S, Weichenhan D, Braun C, Dreßen M, Jacobs AR, Lahm H, Doenst T, Backofen R, Krane M, Gelb BD, Hein L (2018) Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo. Nat Commun, 9, 391, 1-14
Abstract

Harris NA, Isaac AT, Günther A, Merkel K, Melchior J, Xu M, Eguakun E, Perez R, Nabit BP, Flavin S, Gilsbach R, Shonesy B, Hein L, Abel T, Baumann A, Matthews R, Centanni SW, Winder DG (2018) Dorsal BNST α_2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors. J Neurosci, 38, 922-42
Abstract

Kremer M, Yalcin I, Goumon Y, Wurtz X, Nexon L, Daniel D, Megat S, Ceredig RA, Ernst C, Turecki G, Chavant V, Theroux JF, Lacaud A, Joganah LE, Lelievre V, Massotte D, Lutz PE, Gilsbach R, Salvat E, Barrot M (2018) A dual noradrenergic mechanism for the relief of neuropathic allodynia by the antidepressant drugs duloxetine and amitriptyline. J Neurosci, 38, 9934-54
Abstract

Lother A, Bergemann S, Deng L, Moser M, Bode C, Hein L (2018) Cardiac Endothelial Cell Transcriptome. Arterioscler Thromb Vasc Biol, 38, 566-74
Abstract

Lother A, Bergemann S, Kowalski J, Huck M, Gilsbach R, Bode C, Hein L (2018) Inhibition of the cardiac myocyte mineralocorticoid receptor ameliorates doxorubicin-induced cardiotoxicity. Cardiovasc Res, 114, 282–90
Abstract

Nührenberg TG, Cederqvist M, Marini F, Stratz C, Grüning BA, Trenk D, Binder H, Gilsbach R, Neumann FJ, Hein L (2018) Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome. Biomed Res Int, 2018, 8989252, 1-9
Abstract

Rommel C, Rösner S, Lother A, Barg M, Schwaderer M, Gilsbach R, Bömicke T, Schnick T, Mayer S, Doll S, Hesse M, Kretz O, Stiller B, Neumann FJ, Mann M, Krane M, Fleischmann BK, Ravens U, Hein L (2018) The Transcription Factor ETV1 Induces Atrial Remodeling and Arrhythmia. Circ Res, 123, 550-63
Abstract

Rafei-Shamsabadi DA, van de Poel S, Dorn B, Kunz S, Martin SF, Klose CSN, Arnold SJ, Tanriver Y, Ebert K, Diefenbach A, Halim TYF, McKenzie ANJ, Jakob T (2018) Lack of Type 2 Innate Lymphoid Cells Promotes a Type I-Driven Enhanced Immune Response in Contact Hypersensitivity. J Invest Dermatol, 138, 1962-72
Abstract

Wolff J, Bhardwaj V, Nothjunge S, Richard G, Renschler G, Gilsbach R, Manke T, Backofen R, Ramírez F, Grüning BA (2018) Galaxy HiCExplorer: a web server for reproducible Hi-C data analysis, quality control and visualization. Nucleic Acids Res, 46, W11-6
Abstract

2017 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Barthas F, Humo M, Gilsbach R, Waltisperger E, Karatas M, Leman S, Hein L, Belzung C, Boutillier AL, Barrot M, Yalcin I (2017) Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression. Biol Psychiatry, 82, 370-9
Abstract

Hofherr A, Busch T, Huber N, Nold A, Bohn A, Viau A, Bienaimé F, Kuehn EW, Arnold SJ, Köttgen M (2017) Efficient genome editing of differentiated renal epithelial cells. Pflugers Arch, 469, 303-11
Abstract

Kaminski MM, Tosic J, Pichler R, Arnold SJ, Lienkamp SS (2017) Engineering kidney cells: reprogramming and directed differentiation to renal tissues. Cell Tissue Res, 369, 185-97
Abstract

Koentges C, Pepin ME, Müsse C, Pfeil K, Alvarez SVV, Hoppe N, Hoffmann MM, Odening KE, Sossalla S, Zirlik A, Hein L, Bode C, Wende AR, Bugger H (2017) Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans. Basic Res Cardiol, 113, 8, 1-17
Abstract

Krohmer A, Brehm M, Auwärter V, Szabo B (2017) Pregnenolone does not interfere with the effects of cannabinoids on synaptic transmission in the cerebellum and the nucleus accumbens. Pharmacol Res, 123, 51-61
Abstract

Nothjunge S, Nührenberg TG, Grüning BA, Doppler SA, Preissl S, Schwaderer M, Rommel C, Krane M, Hein L, Gilsbach R (2017) DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes. Nat Commun, 8, 1667, 1-9
Abstract

Nussbaum K, Burkhard SH, Ohs I, Mair F, Klose CSN, Arnold SJ, Diefenbach A, Tugues S, Becher B5 (2017) Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs. J Exp Med, 214, 2331-47
Abstract

Pfurr S, Chu YH, Bohrer C, Greulich F, Beattie R, Mammadzada K, Hils M, Arnold SJ, Taylor V, Schachtrup K, Uhlenhaut NH, Schachtrup C (2017) The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development. Development, 144, 3917-31
Abstract

Probst S, Arnold SJ (2017) Eomesodermin - At Dawn of Cell Fate Decisions During Early Embryogenesis. Curr Top Dev Biol, 122, 93-115
Abstract

Probst S, Daza RA, Bader N, Hummel JF, Weiß M, Tanriver Y, Hevner RF, Arnold SJ (2017) A dual-fluorescence reporter in the Eomes locus for live imaging and medium-term lineage tracing. Genesis, 55, e23043, 1-9
Abstract

Raab S, Klingenstein M, Möller A, Illing A, Tosic J, Breunig M, Kuales G, Linta L, Seufferlein T, Arnold SJ, Kleger A, Liebau S (2017) Reprogramming to pluripotency does not require transition through a primitive streak-like state. Sci Rep, 7, 16543, 1-10
Abstract

2016 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Beetz N, Rommel C, Schnick T, Neumann E, Lother A, Monroy-Ordonez EB, Zeeb M, Preissl S, Gilsbach R, Melchior-Becker A, Rylski B, Stoll M, Schaefer L, Beyersdorf F, Stiller B, Hein L (2016) Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload. J Mol Cell Cardiol, 101, 145-55
Abstract

Chatterjee A, Seyfferth J, Lucci J, Gilsbach R, Preissl S, Böttinger L, Mårtensson CU, Panhale A, Stehle T, Kretz O, Sahyoun AH, Avilov S, Eimer S, Hein L, Pfanner N, Becker T, Akhtar A (2016) MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria. Cell, 167, 722-38
Abstract

Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, Klose M, Arnold SJ, Habermann A, Bräuniger R, Rinschen MM, Völker L, Bregenzer A, Rubbenstroth D, Boerries M, Kerjaschki D, Miner JH, Walz G, Benzing T, Fornoni A, Frangakis AS, Huber TB (2016) A flexible, multi-layered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight, 1, e86177, 1-10
Abstract

Gupta SK, Foinquinos A, Thum S, Remke J, Zimmer K, Bauters C, de Groote P, Boon RA, de Windt LJ, Preissl S, Hein L, Batkai S, Pinet F, Thum T (2016) Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction. J Am Coll Cardiol, 68, 1557-71
Abstract

Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS (2016) Direct Reprogramming of Fibroblasts into Renal Tubular Epithelial Cells by Defined Transcription Factors. Nat Cell Biol, 18, 1269-80
Abstract

Koentges C, Pfeil K, Meyer-Steenbuck M, Lother A, Hoffmann MM, Odening KE, Hein L, Bode C, Bugger H (2016) Preserved recovery of cardiac function following ischemia-reperfusion in mice lacking SIRT3. Can J Physiol Pharmacol, 94, 72-80
Abstract

Kranzhöfer DK, Gilsbach R, Grüning BA, Backofen R, Nührenberg TG, Hein L (2016) 5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte Maturation. PLoS ONE, 11, e0166575, 1-23
Abstract

Lindau A, Härdtner C, Hergeth SP, Blanz KD, Dufner B, Hoppe N, Anto-Michel N, Kornemann J, Zou J, Gerhardt LM, Heidt T, Willecke F, Geis S, Stachon P, Wolf D, Libby P, Swirski FK, Robbins CS, McPheat W, Hawley S, Braddock M, Gilsbach R, Hein L, von Zur Mühlen C, Bode C, Zirlik A, Hilgendorf I (2016) Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression. Basic Res Cardiol, 111, 20, 1-11
Abstract

Lother A, Fürst D, Bergemann S, Gilsbach R, Grahammer F, Huber TB, Hilgendorf I, Bode C, Moser M, Hein L (2016) Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure. Hypertension, 67, 130-8
Abstract

Lother A, Hein L (2016) Pharmacology of Heart Failure: From Basic Science to Novel Therapies. Pharmacol Ther, 166, 136-49
Abstract

Lother A, Hein L (2016) Vascular Mineralocorticoid Receptors: Linking Risk Factors, Hypertension, and Heart Disease. Hypertension, 68, 6-10
Abstract

Mihalas AB, Elsen GE, Bedogni F, Daza RA, Ramos-Laguna KA, Arnold SJ, Hevner RF (2016) Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Reports, 16, 92-105
Abstract

Ohs I, van den Broek M, Nussbaum K, Münz C, Arnold SJ, Quezada SA, Tugues S, Becher B (2016) Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun, 7, 13708, 1-12
Abstract

Plačkić J, Preissl S, Nikonova Y, Pluteanu F, Hein L, Kockskämper J (2016) Enhanced nucleoplasmic Ca²⁺ signaling in ventricular myocytes from young hypertensive rats. J Mol Cell Cardiol, 101, 58–68
Abstract

Zadori ZS, Toth VE, Feher A, Al-Khrasani M, Puskar Z, Kozsurek M, Timar J, Tabi T, Helyes Z, Hein L, Holzer P, Gyires K (2016) Inhibition of α_2A-adrenoceptors ameliorates DSS-induced acute intestinal inflammation in mice. J Pharmacol Exp Ther, 358, 483-91
Abstract

2015 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Abe P, Molnár Z, Tzeng YS, Lai DM, Arnold SJ, Stumm R (2015) Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling. J Neurosci, 35, 13053-63
Abstract

Anlauf M, Hein L, Hense HW, Köbberling J, Lasek R, Leidl R, Schöne-Seifert B (2015) Complementary and alternative drug therapy versus science-oriented medicine. Ger Med Sci, 13, 1-23
Abstract

Hein L (2015) The neuroendocrine adrenergic system and cardiovascular function, In: The Cardiovascular Adrenergic System, Lymperopoulos A (Ed.), Springer International Publishing, 117-32
Abstract

Koentges C, König A, Pfeil K, Hölscher ME, Schnick T, Wende AR, Schrepper A, Cimolai MC, Kersting S, Hoffmann MM, Asal J, Osterholt M, Odening KE, Doenst T, Hein L, Abel ED, Bode C, Bugger H (2015) Myocardial mitochondrial dysfunction in mice lacking adiponectin receptor 1. Basic Res Cardiol, 110, 37, 1-17
Abstract

Koentges C, Pfeil K, Schnick T, Wiese S, Dahlbock R, Cimolai MC, Meyer-Steenbuck M, Cenkerova K, Hoffmann MM, Jaeger C, Odening KE, Kammerer B, Hein L, Bode C, Bugger H (2015) SIRT3 deficiency impairs mitochondrial and contractile function in the heart. Basic Res Cardiol, 110, 36, 1-20
Abstract

Lother A, Moser M, Bode C, Feldman RD, Hein L (2015) Mineralocorticoids in the heart and vasculature: new insights for old hormones. Annu Rev Pharmacol Toxicol, 55, 289-312
Abstract

Lupar E, Brack M, Garnier L, Laffont S, Rauch KS, Schachtrup K, Arnold SJ, Guéry JC, Izcue A (2015) Eomesodermin Expression in CD4+ T Cells Restricts Peripheral Foxp3 Induction. J Immunol, 195, 4742-52
Abstract

Mayer SC, Gilsbach R, Preissl S, Monroy Ordonez EB, Schnick T, Beetz N, Lother A, Rommel C, Ihle H, Bugger H, Rühle F, Schrepper A, Schwarzer M, Heilmann C, Bönisch U1, Gupta SK, Wilpert J, Kretz O, von Elverfeldt D, Orth J, Aktories K, Beyersdorf F, Bode C, Stiller B, Krüger M, Thum T, Doenst T, Stoll M, Hein L (2015) Adrenergic repression of the epigenetic reader MeCP2 facilitates cardiac adaptation in chronic heart failure. Circ Res, 117, 622-33
Abstract

Nührenberg TG, Hammann N, Schnick T, Preissl S, Witten A, Stoll M, Gilsbach R, Neumann FJ, Hein L (2015) Cardiac myocyte de novo DNA methyltransferases 3a/3b are dispensable for cardiac function and remodeling after chronic pressure overload in mice. PLoS One, 10, e0131019, 1-16
Abstract

Preissl S, Schwaderer M, Raulf A, Hesse M, Gruning BA, Köbele C, Backofen R, Fleischmann BK, Hein L, Gilsbach R (2015) Deciphering the epigenetic code of cardiac myocyte transcription. Circ Res, 117, 413-23
Abstract

Schmid E, Neef S, Berlin C, Tomasovic A, Kahlert K, Nordbeck P, Deiss K, Denzinger S, Herrmann S, Wettwer E, Weidendorfer M, Becker D, Schäfer F, Wagner N, Ergün S, Schmitt JP, Katus HA, Weidemann F, Ravens U, Maack C, Hein L, Ertl G, Müller OJ, Maier LS, Lohse MJ, Lorenz K (2015) Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy. Nat Med, 21, 1298-306
Abstract

Tsai CY, Tsai CY, Arnold SJ, Huang GJ (2015) Ablation of hippocampal neurogenesis in mice impairs the response to stress during the dark cycle. Nat Commun, 6, 8373, 1-7
Abstract

Vähätalo LH, Ruohonen ST, Mäkelä S, Kovalainen M, Huotari A, Mäkelä KA, Määttä JA, Miinalainen I, Gilsbach R, Hein L, Ailanen L, Mattila M, Eerola K, Röyttä M, Ruohonen S, Herzig KH, Savontaus E (2015) Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice. Acta Physiol (Oxf), 213, 902-19
Abstract

Weise M, Vettel C, Spiger K, Gilsbach R, Hein L, Lorenz K, Wieland T, Aktories K, Orth JH (2015) A systemic Pasteurella multocida toxin aggravates cardiac hypertrophy and fibrosis in mice. Cell Microbiol, 17, 1320-31
Abstract

Ye J, Beetz N, O'Keeffe S, Tapia JC, Maepherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T (2015) hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. P Natl Acad Sci USA, 112, E3020-9
Abstract

2014 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Gilsbach R, Preissl S, Grüning BA, Schnick T, Burger L, Benes V, Wurch A, Bönisch U, Günther S, Backofen R, Fleischmann BK, Schübeler D, Hein L (2014) Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease. Nat Commun, 5, 5288, 1-13
Abstract

Hurt CM, Bjork S, Ho VK, Gilsbach R, Hein L, Angelotti T (2014) REEP1 and REEP2 proteins are preferentially expressed in neuronal and neuronal-like exocytotic tissues. Brain Res, 1545, 12-22
Abstract

Nührenberg T, Gilsbach R, Preissl S, Schnick T, Hein L (2014) Epigenetics in cardiac development, function, and disease. Cell Tissue Res, 356, 585-600
Abstract

Strack J, Heni H, Gilsbach R, Hein L, Aktories K, Orth JH (2014) Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin. Mbio, 5, e02190-14
Abstract

2013 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Bohren Y, Tessier LH, Megat S, Petitjean H, Hugel S, Daniel D, Kremer M, Fournel S, Hein L, Schlichter R, Freund-Mercier MJ, Yalcin I, Barrot M (2013) Antidepressants suppress neuropathic pain by a peripheral β2-adrenoceptor mediated anti-TNFα mechanism. Neurobiol Dis, 60, 39-50
Abstract

Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH (2013) Reelin induces EphB activation. Cell Res, 23, 473-90
Abstract

Guenther F, Herr N, Mauler M, Wisch T, Roming F, Hein L, Boeynaems JM, Robaye B, Idzko M, Bode C, Von Zur Muhlen C, Duerschmied D (2013) Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition. J Thromb Haemost, 11, 1154-62
Abstract

Hermanns-Clausen M, Kneisel S, Hutter M, Szabo B, Auwärter V (2013) Acute intoxication by synthetic cannabinoids--four case reports. Drug Test Anal, 5, 790-4
Abstract

Hermanns-Clausen M, Kneisel S, Szabo B, Auwärter V (2013) Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings. Addiction, 108, 534-44
Abstract

Simon AC, Loverdo C, Gaffuri AL, Urbanski M, Ladarre D, Carrel D, Rivals I, Leterrier C, Benichou O, Dournaud P, Szabo B, Voituriez R, Lenkei Z (2013) Activation-dependent plasticity of polarized GPCR distribution on the neuronal surface. J Mol Cell Biol, 5, 250-65
Abstract

Rossler J, Haubold M, Gilsbach R, Juttner E, Schmitt D, Niemeyer CM, Hein L (2013) β₁-Adrenoceptor mRNA level reveals distinctions between infantile hemangioma and vascular malformations. Pediatr Res, 73, 409-13
Abstract

Volkmann I, Kumarswamy R, Pfaff N, Fiedler J, Dangwal S, Holzmann A, Batkai S, Geffers R, Lother A, Hein L, Thum T (2013) MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses. Circ Res, 113, 997-1003
Abstract

Zadori ZS, Feher A, Al-Khrasani M, Lacko E, Toth VE, Brancati SB, Hein L, Matyus P, Gyires K (2013) Imidazoline versus alpha₂-adrenoceptors in the control of gastric motility in mice. Eur J Pharmacol, 705, 61-7
Abstract

2012 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Biermann D, Heilmann A, Didie M, Schlossarek S, Wahab A, Grimm M, Romer M, Reichenspurner H, Sultan KR, Steenpass A, Ergun S, Donzelli S, Carrier L, Ehmke H, Zimmermann WH, Hein L, Boger RH, Benndorf RA (2012) Impact of AT2 receptor deficiency on postnatal cardiovascular development. Plos One 7, e47916, 1-11
Abstract

Broese M, Riemann D, Hein L, Nissen C (2012) α-adrenergic receptor function, arousal and sleep: mechanisms and therapeutic implications. Pharmacopsychiatry 45, 209-16
Abstract

Gilsbach R, Hein L (2012) Are the pharmacology and physiology of α₂ adrenoceptors determined by α₂-heteroreceptors and autoreceptors respectively? Br J Pharmacol, 165, 90-102
Abstract

Henle F, Dehmel M, Leemhuis J, Fischer C, Meyer DK (2012) Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons. Naunyn Schmiedeberg's Arch Pharmacol 385, 171-80
Abstract

Kovacs FE, Knop T, Urbanski MJ, Freiman I, Freiman TM, Feuerstein TJ, Zentner J, Szabo B (2012) Exogenous and endogenous cannabinoids suppress inhibitory neurotransmission in the human neocortex. Neuropsychopharmacol 37, 1104-14
Abstract

Riccio O, Hurni N, Murthy S, Vutskits L, Hein L, Dayer A (2012) Alpha2-adrenergic receptor activation regulates cortical interneuron migration. Eur J Neurosci, 36, 2879-87
Abstract

Ruohonen ST, Ruohonen S, Gilsbach R, Savontaus E, Scheinin M, Hein L (2012) Involvement of α₂-adrenoceptor subtypes A and C in glucose homeostasis and adrenaline-induced hyperglycaemia. Neuroendocrinology, 96, 51-9
Abstract

2011 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Beetz N, Hein L (2011) The physiological roles of phosducin: from retinal function to stress-dependent hypertension. Cell Mol Life Sci, 68, 599-612
Abstract

Brede M, Braeuninger S, Langhauser F, Hein L, Roewer N, Stoll G, Kleinschnitz C (2011) α₂-adrenoceptors do not mediate neuroprotection in acute ischemic stroke in mice. J Cereb Blood Flow Metab, 31, e1-7
Abstract

Broeckel U, Stoll M, Hein L (2011) The identification of phosducin as a novel candidate gene for hypertension and its role in sympathetic activation. Curr Opin Nephrol Hypertens, 20, 118-24
Abstract

Choucair-Jaafar N, Beetz N, Gilsbach R, Yalcin I, Waltisperger E, Freund-Mercier MJ, Monassier L, Hein L, Barrot M (2011) Cardiovascular effects of chronic treatment with a β2-adrenoceptor agonist relieving neuropathic pain in mice. Neuropharmacology, 61, 51-60
Abstract

Faerber G, Barreto-Perreia F, Schoepe M, Gilsbach R, Schrepper A, Schwarzer M, Mohr FW, Hein L, Doenst T (2011) Induction of heart failure by minimally invasive aortic constriction in mice: reduced peroxisome proliferator-activated receptor gamma coactivator levels and mitochondrial dysfunction. J Thorac Cardiovasc Surg, 141, 492-500, 500 e491
Abstract

Fraccarollo D, Berger S, Galuppo P, Kneitz S, Hein L, Schutz G, Frantz S, Ertl G, Bauersachs J (2011) Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction. Circulation, 123, 400-8
Abstract

Gilsbach R, Preissl S, Hein L (2011) [α-adrenoceptors: three subtypes for a broad spectrum of activity]. Pharm Unserer Zeit, 40, 462-8
Abstract

Gilsbach R, Albarran-Juarez J, Hein L (2011) Pre- versus postsynaptic signaling by α₂-adrenoceptors. Curr Top Membr, 67, 139-60
Abstract

Hein L (2011) [Structure and evolution of adrenergic receptors]. Pharm Unserer Zeit, 40, 470-3
Abstract

Hoch H, Stegbauer J, Potthoff SA, Hein L, Quack I, Rump LC, Vonend O (2011) Regulation of renal sympathetic neurotransmission by renal α_2A-adrenoceptors is impaired in chronic renal failure. Br J Pharmacol, 163, 438-46
Abstract

Kovacs FE, Illes P, Szabo B (2011) Purine receptor-mediated endocannabinoid production and retrograde synaptic signaling in the cerebellar cortex Brit J Pharmacol, 162, 974-88
Abstract

Leemhuis J, Bock HH (2011) Reelin modulates cytoskeletal organization by regulating Rho GTPases. Commun Integr Biol 4, 254-7
Abstract

Lother A, Berger S, Gilsbach R, Rosner S, Ecke A, Barreto F, Bauersachs J, Schutz G, Hein L (2011) Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function. Hypertension, 57, 746-54
Abstract

Schneider J, Lother A, Hein L, Gilsbach R (2011) Chronic cardiac pressure overload induces adrenal medulla hypertrophy and increased catecholamine synthesis. Basic Res Cardiol, 106, 591-602
Abstract

Shujaa N, Al-Khrasani M, Zadori ZS, Rossi M, Matyus P, Nemeth J, Hein L, Gyires K (2011) α₂-adrenoceptor agonist-induced inhibition of gastric motor activity is mediated by α_2A-adrenoceptor subtype in the mouse. Neurochem Int, 58, 708-13
Abstract

Zadori ZS, Shujaa N, Brancati SB, Hein L, Gyires K (2011) Both α_2B- and α_2C-adrenoceptor subtypes are involved in the mediation of centrally induced gastroprotection in mice. Eur J Pharmacol, 669, 115-20
Abstract

2010 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Brawek B, Löffler M, Wagner K, Huppertz H-J, Wendling A-S, Weyerbrock A, Jackisch R, Feuerstein T (2010) Reactive oxygen species (ROS) in the human neocortex: Role of aging and cognition Brain Res Bull, 81, 484-90
Abstract

Clere N, Corre I, Faure S, Guihot AL, Vessieres E, Chalopin M, Morel A, Coqueret O, Hein L, Delneste Y, Paris F, Henrion D (2010) Deficiency or blockade of angiotensin II type 2 receptor delays tumorigenesis by inhibiting malignant cell proliferation and angiogenesis. Int J Cancer, 127, 2279-91
Abstract

Gilsbach R, Schneider J, Lother A, Schickinger S, Leemhuis J, Hein L (2010) Sympathetic α₂-adrenoceptors prevent cardiac hypertrophy and fibrosis in mice at baseline but not after chronic pressure overload. Cardiovasc Res, 86, 432-42
Abstract

Haubold M, Gilsbach R, Hein L (2010) α_2B-adrenoceptor deficiency leads to postnatal respiratory failure in mice. J Biol Chem, 285, 34213-34219
Abstract

Jones BC, Ben-Hamida S, Pereira de Vasconcelos A, Kelche C, Lazarus C, Jackisch R, Cassel JC (2010) Effects of ethanol and ecstacy on conditioned place preference in the rat. J Psychopharmacol, 24, 275-9
Abstract

Khakpay R, Polster D, Köles L, Skorinkin A, Szabo B, Wirkner K, Illes P (2010) Potentiation of the glutamatergic synaptic input to rat locus coeruleus neurons by P2X7 receptors. Purinerg Signal, 6, 349-59
Abstract

Leemhuis J, Bouche E, Frotscher M, Henle F, Hein L, Herz J, Meyer DK, Pichler M, Roth G, Schwan C, Bock HH (2010) Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation. J Neurosci, 30, 14759-72
Abstract

Urbanski MJ, Kovacs FE, Szabo B (2010) Endocannabinoid-mediated synaptically evoked suppression of GABAergic transmisssion in the cerebellar cortex. Neuroscience, 169, 1268-78
Abstract

Yalcin I, Tessier LH, Petit-Demouliere N, Waltisperger E, Hein L, Freund-Mercier MJ, Barrot M (2010) Chronic treatment with agonists of β₂-adrenergic receptors in neuropathic pain. Exp Neurol, 221, 115-21
Abstract

Yanpallewar SU, Fernandes K, Marathe SV, Vadodaria KC, Jhaveri D, Rommelfanger K, Ladiwala U, Jha S, Muthig V, Hein L, Bartlett P, Weinshenker D, Vaidya VA (2010) α₂-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment. J Neurosci, 30, 1096-1109
Abstract

2009 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Albarran-Juarez J, Gilsbach R, Piekorz RP, Pexa K, Beetz N, Schneider J, Nurnberg B, Birnbaumer L, Hein L (2009) Modulation of α₂-adrenoceptor functions by heterotrimeric Gα_i protein isoforms. J Pharmacol Exp Ther, 331, 35-44
Abstract

Baqi Y, Atzler K, Köse M, Glänzel M, Müller CE (2009) High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors. J Med Chem, 52, 3784-93
Abstract

Beetz N, Hein L, Meszaros J, Gilsbach R, Barreto F, Meissner M, Hoppe UC, Schwartz A, Herzig S, Matthes J (2009) Transgenic simulation of human heart failure-like L-type Ca²⁺-channels: implications for fibrosis and heart rate in mice. Cardiovasc Res, 84, 396-406
Abstract

Beetz N, Harrison MD, Brede M, Zong X, Urbanski MJ, Sietmann A, Kaufling J, Lorkowski S, Barrot M, Seeliger MW, Vieira-Coelho MA, Hamet P, Gaudet D, Seda O, Tremblay J, Kotchen TA, Kaldunski M, Nüsing R, Szabo B, Jacob HJ, Cowley AW Jr, Biel M, Stoll M, Lohse MJ, Broeckel U, Hein L (2009) Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. J Clin Invest, 119, 3597-612
Abstract

Benndorf RA, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt-Haupt R, Steinmetz OM, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl RA, Böger RH, Wenzel UO (2009) Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice. Kidney Int, 75, 1039-49
Abstract

Boettger T, Beetz N, Kostin S, Schneider J, Kruger M, Hein L, Braun T (2009) Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest, 119, 2634-47
Abstract

Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W (2009) G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. J Biol Chem, 284, 35040-8
Abstract

Gilsbach R, Roser C, Beetz N, Brede M, Hadamek K, Haubold M, Leemhuis J, Philipp M, Schneider J, Urbanski M, Szabo B, Weinshenker D, Hein L (2009) Genetic dissection of α₂-adrenoceptor functions in adrenergic versus nonadrenergic cells. Mol Pharmacol, 75, 1160-70
Abstract

Hoffmann K, Baqi Y, Morena MS, Glänzel M, Müller CE, von Kügelgen (2009) Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor. J Pharmacol Exp Ther, 331, 648-55
Abstract

Jackisch R, Förster S, Kammerer M, Rothmaier AK, Ehret A, Zentner J, Feuerstein TJ (2009) Inhibitory potency of choline esterase inhibitors on acetylcholine release and choline esterase activity in fresh specimens of human and rat neocortex. J Alzheimers Dis, 16, 635-47
Abstract

Mantovani M, Dooley D, Weyerbrock A, Jackisch R, Feuerstein T (2009) Differential inhibitory effects of drugs acting at the noradrenaline and 5-hydroxytryptamine transporters in rat and human neocortical synaptosomes. Brit J Pharmacol, 158, 1848-56
Abstract

Philipp M, Caron MG (2009) Hedgehog signaling: Is Smo a G protein-coupled receptor? Curr Biol, 19, R125-7
Abstract

Rutz S, Majchrzak M, Siedschlag V, Barbelivien A, Harati H, Rothmaier AK, Feuerstein TJ, Jackisch R, Cassel JC (2009) The modulation of striatal dopamine release correlates with water-maze performance in aged rats Neurobiol Aging, 30, 957-72
Abstract

Schmitt JP, Ahmad F, Lorenz K, Hein L, Schulz S, Asahi M, Maclennan DH, Seidman CE, Seidman JG, Lohse MJ (2009) Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca²⁺-ATPase inhibition. Circulation, 119, 436-44
Abstract

Stoll C, Eltze M, Lambrecht G, Zentner J, Feuerstein TJ, Jackisch R (2009) Functional characterization of muscarinic autoreceptors in rat and human neocortex. J Neurochem, 110, 837-47
Abstract

Starke K (2009) On pharmacologists and pharmacology. Naunyn-Schmiedeberg's Arch Pharmacol, 380, 465-71
Abstract

Urbanski MJ, Kovacs FE, Szabo B (2009) Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling. Synapse, 63, 643-52
Abstract

Yalcin I, Tessier LH, Petit-Demouliere N, Doridot S, Hein L, Freund-Mercier MJ, Barrot M (2009) β₂-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain. Neurobiol Dis, 33, 386-94
Abstract

Yalcin I, Choucair-Jaafar N, Benbouzid M, Tessier LH, Muller A, Hein L, Freund-Mercier MJ, Barrot M (2009) β₂-adrenoceptors are critical for antidepressant treatment of neuropathic pain. Ann Neurol, 65, 218-25
Abstract

Beetz N, Hein L (2008) Adrenaline and noradrenaline In: Bader M (Hrsg.): Cardiovascular Hormone Systems Heidelberg: Springer, 2008
Abstract

Dahmani S, Paris A, Jannier V, Hein L, Rouelle D, Scholz J, Gressens P, Mantz J (2008) Dexmedetomidine increases hippocampal phosphorylated extracellular signal-regulated protein kinase 1 and 2 content by an α₂-adrenoceptor-independent mechanism: evidence for the involvement of imidazoline I1 receptors. Anesthesiology, 108, 457-66
Abstract

Fuentes EO, Leemhuis J, Stark GB, Lang EM (2008) Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells. Journal of Brachial Plexus and Peripheral Nerve Injury, 3, 19-30
Abstract

Gilsbach R, Hein L (2008) Presynaptic metabotropic receptors for acetylcholine and adrenaline/noradrenaline. Handb Exp Pharmacol, 261-88
Abstract

Haubold, Hein L (2008) [α₁ adrenergic antagonists]. Pharm Unserer Zeit, 37, 290-5
Abstract

Haenisch B, Linsel K, Brüss M, Gilsbach R, Propping P, Nöthen MM, Rietschel M, Fimmers R, Maier W, Zobel A, Höfels S, Guttenthaler V, Göthert M, Bönisch H (2008) Association of major depression with rare functional variants in norepinephrine transporter and serotonin-1A-receptor genes. Am J Med Genet B, 150, 1013-16
Abstract

Haenisch B, Gilsbach R, Bönisch H (2008) Neurotropin and neuropeptide expression in mouse brain is regulated by knockout of the norepinephrine transporter. J Neural Transm, 115, 973-82
Abstract

Jackisch R, Gansser S, Cassel JC (2008) Noradrenergic denervation facilitates the release of acetylchoine and serotonin in the hippocampus: Towards a mechanism underlying upregulations described in MCI patents? Exp Neurol, 213, 345-53
Abstract

Philipp M, Fralish GB, Meloni AR, Chen W, MacInnes AW, Barak LS, Caron MG (2008) Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase. Mol Biol Cell, 19, 5478-89
Abstract

Riegert C, Rothmaier AK, Leemhuis J, Sexton T, Neumaier JF, Caassel J-C, Jackisch R (2008) Increased expression of 5-HT_1B receptors by Herpes simplex virus gene transfer in septal neurons: New in vitro and in vivo models to study 5-HT_1B receptor function. Brain Res Bull, 76, 439-53
Abstract

Riegert C, Wedekind F, Ben Hamida S, Rutz S, Rothmaier AK, Jones BC, Cassel J-C, Jackisch K (2008) Effects of ethanol and 3,4-methylenedioxymethamphetamine (MDMA) alone or in combination on spontaneous and evoked overflow of dopamine, serotonin and acetylcholine in striatal slices of the rat brain. Int J Neuropsychoph, 11, 743-63
Abstract

2007 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Birthelmer A, Ehret A, Riegert C, Rothmaier AK, Lemhuis J, Jackisch R (2007) Modulation of electrically evoked serotonin release in cultured rat raphe neurons. J Neurochem, 100, 1613-25
Abstract

Cassel J-C, Lazaris A, Birthelmer A, Jackisch R (2007) Spatial reference- (not working- or procedural-) memory performance of aged rats in the water maze predicts the magnitude of sulpiride-induced facilitation of acetylcholine release by striatal slices. Neurobiol Aging, 28, 1270-85
Abstract

Ehret A, Birthelmer A, Rutz S, Riegert C, Rothmaier AK, Jackisch R (2007) Agonist-mediated regulation of presynaptic receptor function during development of rat septal neurons in culture. J Neurochem, 102, 1071-82
Abstract

Gilsbach R, Brede M, Beetz N, Moura E, Muthig V, Gerstner C, Barreto F, Neubauer S, Vieira-Coelho MA, Hein L (2007) Heterozygous α_2C-adrenoceptor-deficient mice develop heart failure after transverse aortic constriction. Cardiovasc Res, 75, 728-37
Abstract

Hullin R, Matthes J, von Vietinghoff S, Bodi I, Rubio M, D'Souza K, Friedrich Khan I, Rottländer D, Hoppe UC, Mohacsi P, Schmitteckert E, Gilsbach R, Bünemann M, Hein L, Schwartz A, Herzig S (2007) Increased expression of the auxiliary β₂-subunit of ventricular L-type Ca²⁺ channels leads to single-channel activity characteristic of heart failure. PLoS One, 2, e292, 1-11
Abstract

Knaus AE, Muthig V, Schickinger S, Moura E, Beetz N, Gilsbach R, Hein L (2007) α₂-adrenoceptor subtypes--unexpected functions for receptors and ligands derived from gene-targeted mouse models. Neurochem Int, 51, 277-81
Abstract

Knaus A, Zong X, Beetz N, Jahns R, Lohse MJ, Biel M, Hein L (2007) Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine. Circulation, 115, 872-80
Abstract

Kuba K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, Leschnik M, Leibbrandt A, Markovic M, Schwaighofer J, Beetz N, Musialek R, Neely GG, Komnenovic V, Kolm U, Metzler B, Ricci R, Hara H, Meixner A, Nghiem M, Chen X, Dawood F, Wong KM, Sarao R, Cukerman E, Kimura A, Hein L, Thalhammer J, Liu PP, Penninger JM (2007) Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res, 101, e32-42
Abstract

Munk VC, Sanchez de Miguel L, Petrimpol M, Butz N, Banfi A, Eriksson U, Hein L, Humar R, Battegay EJ (2007) Angiotensin II induces angiogenesis in the hypoxic adult mouse heart in vitro through an AT₂-B2 receptor pathway. Hypertension, 49, 1178-85
Abstract

Muck A, Gilsbach R, Löbbe-Werner S, Brüss M, Bönisch H (2007) Molecular cloning and functional expression of the murine noradrenaline transporter. Naunyn-Schmiedeberg's Arch Pharmacol, 376, 65-71
Abstract

Muthig V, Gilsbach R, Haubold M, Philipp M, Ivacevic T, Gessler M, Hein L (2007) Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of α_2B-adrenoceptor deficient mice. Circ Res, 101, 682-91
Abstract

Paris A, Hein L, Brede M, Brand PA, Scholz J, Tonner PH (2007) The anesthetic effects of etomidate: species-specific interaction with α₂-adrenoceptors. Anesth Analg, 105, 1644-9
Abstract

Rutz R, Riegert C, Rothmaier AK, Jackisch R (2007) Presynaptic modulation of 5-HT release in the rat septal region. Neuroscience, 146, 643-158
Abstract

Starke K (2007) In memoriam: Ullrich Georg Trendelenburg (31 December 1922 - 21 November 2006). Naunyn-Schmiedeberg's Arch Pharmacol, 375, 231-40
Abstract

Vonend O, Habbel S, Stegbauer J, Roth J, Hein L, Rump LC (2007) α_2A-adrenoceptors regulate sympathetic transmitter release in mice kidneys. Br J Pharmacol, 150, 121-7
Abstract

2006 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Berger B, Rothmaier AK, Wedekind F, Zentner J, Feuerstein TJ, Jackisch R (2006) Presynaptic opioid receptors on noradrenergic and serotonergic neurons in the human as compared to the rat neocortex. Brit J Pharmacol, 148, 795-806
Abstract

Engler B, Freiman I, Urbanski M, Szabo B (2006) Effects of exogenous and endogenous cannabinoids on GABAergic neurotransmission between the caudate-putamen and the globus pallidus in the mouse. J Pharmacol Exp Ther, 316, 608-17
Abstract

Freiman I, Anton A, Monyer H, Urbanski M, Szabo B (2006) Analysis of the effects of cannabinoids on identified synaptic connections in the caudate-putamen by paired recordings in transgenic mice. J Physiol London, 575, 798-806
Abstract

Guijarro C, Rutz S, Rothmaier K, Turiault M, Zhi Q, Naumann T, Frotscher M, Tronche F, Jackisch R, Kretz O (2006) Maturation and maintenance of cholinergic medial septum neurons require glucocorticoid receptor signaling. J Neurochem, 97, 747-58
Abstract

Hallhuber M, Burkard N, Wu R, Buch MH, Engelhardt S, Hein L, Neyses L, Schuh K, Ritter O (2006) Inhibition of nuclear import of calcineurin prevents myocardial hypertrophy. Circ Res, 99, 626-35
Abstract

Hein L (2006) Adrenoceptors and signal transduction in neurons. Cell Tissue Res, 326, 541-51
Abstract

Löffler M, Bubl B, Huethe F, Hubbe U, McIntosh JM, Jackisch R, Feuerstein TJ (2006) Dopamine release in human neocortical slices: Characterization of inhibitory autoreceptors and of nicotinic acetylcholine receptor-evoked release. Brain Res Bull, 68, 361-73
Abstract

Moura E, Afonso J, Hein L, Vieira-Coelho MA (2006) α₂-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice. Br J Pharmacol, 149, 1049-58
Abstract

Paris A, Mantz J, Tonner PH, Hein L, Brede M, Gressens P (2006) The effects of dexmedetomidine on perinatal excitotoxic brain injury are mediated by the α_2A-adrenoceptor subtype. Anesth Analg, 102, 456-61
Abstract

Pozgajova M, Sachs UJ, Hein L, Nieswandt B (2006) Reduced thrombus stability in mice lacking the α_2A-adrenergic receptor. Blood, 108, 510-4
Abstract

Regitz-Zagrosek V, Hocher B, Bettmann M, Brede M, Hadamek K, Gerstner C, Lehmkuhl HB, Hetzer R, Hein L (2006) α_2C-adrenoceptor polymorphism is associated with improved event-free survival in patients with dilated cardiomyopathy. Eur Heart J, 27, 454-9
Abstract

Rutz S, Riegert C, Rothmaier AK, Buhot MC, Cassel JC, Jackisch R (2006) Presynaptic serotonergic modulation of 5-HT and acetylcholine release in the hippocampus and the cortex of 5-HT_1B-receptor knockout mice. Brain Res Bull, 70, 81-93
Abstract

Szabo B, Urbanski MJ, Bisogno T, Di Marzo V, Mendiguren A, Baer WU, Freiman I (2006) Depolarization-induced retrograde synaptic inhibition in the cerebellar cortex is mediated by 2-arachidonylglycerol. J Physiol-London, 577, 263-80
Abstract

Stork S, Boivin V, Horf R, Hein L, Lohse MJ, Angermann CE, Jahns R (2006) Stimulating autoantibodies directed against the cardiac β₁-adrenergic receptor predict increased mortality in idiopathic cardiomyopathy. Am Heart J, 152, 697-704
Abstract

2005 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

Cassel JC, Schweizer T, Lazaris A, Knorle R, Birthelmer A, Godtel-Armbrust U, Forstermann U, Jackisch R (2005) Cognitive deficits in aged rats correlate with levels of L-arginine, not with nNOS expression or 3,4-DAP-evoked transmitter release in the frontoparietal cortex evoked transmitter release in the frontoparietal cortex Eur Neuropsychopharmacol, 15, 163-75
Abstract

Cassel JC, Riegert C, Rutz S, Koenig J, Rothmaier K, Cosquer B, Lazarus C, Birthelmer A, Jeltsch H, Jones BC, Jackisch R (2005) Ethanol, 3,4-methylenedioxymethamphetamine (ecstasy) and their combination: long-term behavioral, neurochemical and neuropharmacological effects in the rat. Neuropsychopharmacology, 30, 1870-82
Abstract

Freiman I, Szabo B (2005) Cannabinoids depress excitatory neurotransmission between the subthalamic nucleus and the globus pallidus. Neuroscience, 133, 305-13
Abstract

Glänzel M, Bültmann R, Starke K, Frahm AW (2005) Structure-activity relationships of novel P2-receptor antagonists structurally related to Reactive Blue 2. Eur J Med Chem, 40, 1272-6
Abstract

Hein L (2005) Angiotensin II and cell-matrix adhesion: PKCε is essential. Cardiovasc Res, 67, 6-8
Abstract

Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM (2005) Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature, 436, 112-6
Abstract

Most P, Boerries M, Eicher C, Schweda C, Volkers M, Wedel T, Sollner S, Katus HA, Remppis A, Aebi U, Koch WJ, Schoenenberger CA (2005) Distinct subcellular location of the Ca²⁺ binding protein S100A1 differentially modulates Ca²⁺ cycling in ventricular rat cardiomyocytes. J Cell Sci, 118, 421-31
Abstract

Pfitzer T, Niederhoffer N, Szabo B (2005) Search for an endogenous cannabinoid mediated effect in the sympathetic nervous system. Naunyn-Schmiedeberg's Arch Pharmacol, 371, 9-17
Abstract

Schoenenberger CA, Buchmeier S, Boerries M, Sutterlin R, Aebi U, Jockusch BM (2005) Conformation specific antibodies reveal distinct actin structures in the nucleus and the cytoplasm. J Struct Biol J Struct Biol, 152, 157-68
Abstract

Szabo B, Schlicker E (2005) Effects of cannabinoids on neurotransmission. In: Pertwee RG (Hrsg.): Cannabinoids, Handbook of Experimental Pharmacology, Vol. 168, pp 327-365, Springer, Berlin, 365, 327-65
Abstract

Trendelenburg AU, Meyer A, Wess J, Starke K (2005) Distinct mixtures of muscarinic receptor subtypes mediate inhibition of noradrenaline release in different mouse peripheral tissues, as studied with receptor knockout mice. Brit J Pharmacol, 145, 1153-9
Abstract

29 January 2024