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2024 2024 2023 2022 2021 2020 2019

Hartmann B, Fleischhauer L, Nicolau M, Jensen THL, Taran FA, Clausen-Schaumann H, Reuten R (2024) Profiling native pulmonary basement membrane stiffness using atomic force microscopy. Nat Protoc, 19, 1498-528
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Ma J, Wehrle J, Frank D, Lorenzen L, Popp C, Driever W, Grosse R, Jessen HJ (2024) Intracellular delivery and deep tissue penetration of nucleoside triphosphates using photocleavable covalently bound dendritic polycations. Chem Sci, 15, 6478-87
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Maas-Bauer K, Stell AV, Yan KL, de Vega E, Vinnakota JM, Unger S, Núñez N, Norona J, Talvard-Balland N, Koßmann S, Schwan C, Miething C, Martens US, Shoumariyeh K, Nestor RP, Duquesne S, Hanke K, Rackiewicz M, Hu Z, El Khawanky N, Taromi S, Andrlova H, Faraidun H, Walter S, Pfeifer D, Follo M, Waldschmidt J, Melchinger W, Rassner M, Wehr C, Schmitt-Graeff A, Halbach S, Liao J, Häcker G, Brummer T, Dengjel J, Andrieux G, Grosse R, Tugues S, Blazar BR, Becher B, Boerries M, Zeiser R (2024) ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nat Commun, 15, 446, 1-15
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Papatheodorou P, Minton NP, Aktories K, Barth H (2024) An Updated View on the Cellular Uptake and Mode-of-Action of Clostridioides difficile Toxins. Adv Exp Med Biol, 1435, 219-47
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Schneider S, Wirth C, Jank T, Hunte C, Aktories K (2024) Tyrosine-modifying glycosylation by Yersinia effectors. J Biol Chem, 107331, Epub ahead of print
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Tsvilovskyy V, Ottenheijm R, Kriebs U, Schütz A, Diakopoulos KN, Jha A, Bildl W, Wirth A, Böck J, Jaślan D, Ferro I, Taberner FJ, Kalinina O, Hildebrand S, Wissenbach U, Weissgerber P, Vogt D, Eberhagen C, Mannebach S, Berlin M, Kuryshev V, Schumacher D, Philippaert K, Camacho-Londoño JE, Mathar I, Dieterich C, Klugbauer N, Biel M, Wahl-Schott C, Lipp P, Flockerzi V, Zischka H, Algül H, Lechner SG, Lesina M, Grimm C, Fakler B, Schulte U, Muallem S, Freichel M (2024) OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage. J Clin Invest, 134, e169428, 1-15
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Ulferts S, Lopes M, Miyamoto K, Grosse R (2024) Nuclear actin dynamics and functions at a glance. J Cell Sci, 137, jcs261630, 1-7
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2023 2024 2023 2022 2021 2020 2019

Aktories K (2023) Clostridioides difficile infection drives neuronal inflammation. Nature, 622, 465-7
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Aktories K (2023) From signal transduction to protein toxins-a narrative review about milestones on the research route of C. difficile toxins. Naunyn Schmiedebergs Arch Pharmacol, 396, 173-90
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Behren S, Schorlemer M, Schmidt G, Aktories K, Westerlind U (2023) Antibodies Directed Against GalNAc- and GlcNAc-O-Tyrosine Posttranslational Modifications - a New Tool for Glycoproteomic Detection. Chemistry, 29, e202300392, 1-13
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Francois L, Boskovic P, Knerr J, He W, Sigismondo G, Schwan C, More TH, Schlotter M, Conway ME, Krijgsveld J, Hiller K, Grosse R, Lichter P, Radlwimmer B (2023) BCAT1 redox function maintains mitotic fidelity. Cell Rep, 42, 112217, Erratum for 41, 111524
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Frank D, Moussie JC, Ulferts S, Lorenzen L, Schwan C, Grosse R (2023) Vesicle-Associated Actin Assembly by Formins Promotes TGFβ-Induced ANGPTL4 Trafficking, Secretion and Cell Invasion. Adv Sci (Weinh), 10, e2204896, 1-9
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Jakob D, Schmoor C, Reuten R, Frevert ML, Dannehl D, Jansen L, Hermann S, Jungmann P, Hartkopf AD, Juhasz-Böss I, Taran FA (2023) Characteristics, Treatment Patterns and Survival of International Federation of Gynecology and Obstetrics Stage IV Epithelial Ovarian Cancer – A Population-Based Study. Cancers (Basel), 15, 5676, 1-13
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Just A, Mallmann RT, Grossmann S, Sleman F, Klugbauer N (2023) Two-pore channel protein TPC1 is a determining factor for the adaptation of proximal tubular phosphate handling. Acta Physiol (Oxf), 237, e13914, 1-17
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Knerr J, Werner R, Schwan C, Wang H, Gebhardt P, Grötsch H, Caliebe A, Spielmann M, Holterhus PM, Grosse R, Hornig NC (2023) Formin-mediated nuclear actin at androgen receptors promotes transcription. Nature, 617, 616-22
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Lan C, Kim J, Ulferts S, Aprile-Garcia F, Weyrauch S, Anandamurugan A, Grosse R, Sawarkar R, Reinhardt A, Hugel T (2023) Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation. Nat Commun, 14, 4831, 1-8
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Lorenzen L, Frank D, Schwan C, Grosse R (2023) Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation. Biomolecules, 13, 548, 1-14
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Meier M, Gupta M, Akgül S, McDougall M, Imhof T, Nikodemus D, Reuten R, Moya-Torres A, To V, Ferens F, Heide F, Padilla-Meier GP, Kukura P, Huang W, Gerisch B, Mörgelin M, Poole K, Antebi A, Koch M, Stetefeld J (2023) The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation. Nat Commun, 14, 1226, 1-18
Abstract

Ojasalu K, Lieber S, Sokol AM, Nist A, Stiewe T, Bullwinkel I, Finkernagel F, Reinartz S, Müller-Brüsselbach S, Grosse R, Graumann J, Müller R (2023) The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis. Theranostics, 13, 1921-48
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Palumbieri MD, Merigliano C, González-Acosta D, Kuster D, Krietsch J, Stoy H, von Känel T, Ulferts S, Welter B, Frey J, Doerdelmann C, Sanchi A, Grosse R, Chiolo I, Lopes M (2023) Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity. Nat Commun, 14, 7819, 1-15
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Rafaeva M, Jensen ARD, Horton ER, Zornhagen KW, Strøbech JE, Fleischhauer L, Mayorca-Guiliani AE, Nielsen SR, Grønseth DS, Kuś F, Schoof EM, Arnes L, Koch M, Clausen-Schaumann H, Izzi V, Reuten R, Erler JT (2023) Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression. Front Immunol, 14, 1154528, 1-12
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Su C, Rodriguez-Franco M, Lace B, Nebel N, Hernandez-Reyes C, Liang P, Schulze E, Mymrikov EV, Gross NM, Knerr J, Wang H, Siukstaite L, Keller J, Libourel C, Fischer AAM, Gabor KE, Mark E, Popp C, Hunte C, Weber W, Wendler P, Stanislas T, Delaux PM, Einsle O, Grosse R, Römer W, Ott T (2023) Stabilization of membrane topologies by proteinaceous remorin scaffolds. Nat Commun, 14, 323, 1-16
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Wardas B, Schneider JG, Klugbauer N, Flockerzi V, Beck A (2023) Englerin A inhibits T-type CaV channels at low-micromolar concentrations. Mol Pharmacol, 104, 144-53
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2022 2024 2023 2022 2021 2020 2019

Aigal S, Omidvar R, Stober K, Ziegelbauer J, Eierhoff T, Schampera JN, Römer W, Schwan C (2022) Septin barriers protect mammalian host cells against Pseudomonas aeruginosa invasion. Cell Rep, 41, 111510, 1-17
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Aktories K (2022) Another surprise in receptor binding of C. difficile toxins. Innovation (Camb), 3, 100261, 1-2
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Aktories K (2022) Treatment of ovarian cancer with modified anthrax toxin. Proc Natl Acad Sci U S A, 119 (32), e2210179119, 1-3
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Cobb AM, De Silva SA, Hayward R, Sek K, Ulferts S, Grosse R, Shanahan CM (2022) Filamentous nuclear actin regulation of PML NBs during the DNA damage response is deregulated by prelamin A. Cell Death Dis, 13, 1042, 1-12
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Francois L, Boskovic P, Knerr J, He W, Sigismondo G, Schwan C, More TH, Schlotter M, Krijgsveld J, Hiller K, Grosse R, Lichter P, Radlwimmer B (2022) BCAT1 redox function maintains mitotic fidelity. Cell Rep, 41, 111524, 1-25
Abstract

Kaleta T, Kern L, Hong SL, Hölzer M, Kochs G, Beer J, Schnepf D, Schwemmle M, Bollen N, Kolb P, Huber M, Ulferts S, Weigang S, Dudas G, Wittig A, Jaki L, Padane A, Lagare A, Salou M, Ozer EA, Nnaemeka N, Odoom JK, Rutayisire R, Benkahla A, Akoua-Koffi C, Ouedraogo AS, Simon-Lorière E, Enouf V, Kröger S, Calvignac-Spencer S, Baele G, Panning M, Fuchs J (2022) Antibody escape and global spread of SARS-CoV-2 lineage A.27. Nat Commun, 13, 1152, 1-13
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Reuten R, Mayorca-Guiliani AE, Erler JT (2022) Matritecture: Mapping the extracellular matrix architecture during health and disease. Matrix Biol Plus, 14, 100102, 1-6
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Schoellkopf J, Mueller T, Hippchen L, Mueller T, Reuten R, Backofen R, Orth J, Schmidt G (2022) Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein 1 (LRP1) as crucial cellular receptor. PLoS Pathog, 18, e1010781, 1-16
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Schwan C, Lang AE, Schlosser A, Fujita-Becker S, AlHaj A, Schröder RR, Faix J, Aktories K, Mannherz HG (2022) Inhibition of Arp2/3 Complex after ADP-Ribosylation of Arp2 by Binary Clostridioides Toxins. Cells, 11, 3661, 1-21
Abstract

Simpson M, Frisbee A, Kumar P, Schwan C, Aktories K, Petri WA (2022) Clostridioides difficile binary toxin (CDT) is recognized by the TLR2/6 heterodimer to induce an NF-κB response. J Infect Dis, 225, 1296-300
Abstract

Zähringer S, Rumpf T, Melesina J, Lang AE, Aktories K, Sippl W, Jung M, Wagner GK (2022) Defined stereoisomers of 2"-amino NAD+ and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase. Bioorg Med Chem, 68, 116875, 1-11
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2021 2024 2023 2022 2021 2020 2019

Grossmann S, Mallmann RT, Klugbauer N (2021) Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways. Cells, 10, 1807, 1-13
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Kowarschik S, Schöllkopf J, Müller T, Tian S, Knerr J, Bakker H, Rein S, Dong M, Weber S, Grosse R, Schmidt G (2021) Yersinia pseudotuberculosis cytotoxic necrotizing factor interacts with glycosaminoglycans. FASEB J, 35, e21647, 1-16
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Li Y, Schön C, Chen CC, Yang Z, Liegl R, Murenu E, Schworm B, Klugbauer N, Grimm C, Wahl-Schott C, Michalakis S, Biel M (2021) TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration. Life Sci Alliance, 4, e202101047, 1-13
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Liang P, Schmitz C, Lace B, Ditengou FA, Su C, Schulze E, Knerr J, Grosse R, Keller J, Libourel C, Delaux PM, Ott T (2021) Formin-mediated bridging of cell wall, plasma membrane, and cytoskeleton in symbiotic infections of Medicago truncatula. Curr Biol, 31, 2712-19
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Müller T, Grossmann S, Mallmann RT, Rommel C, Hein L, Klugbauer N (2021) Two-pore channels affect EGF receptor signaling by receptor trafficking and expression. iScience, 24, 1-30
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Ng'ang'a PN, Siukstaite L, Lang AE, Bakker H, Römer W, Aktories K, Schmidt G (2021) Involvement of N-glycans in binding of Photorhabdus luminescens Tc toxin. Cell Microbiol, 23, e13326, 1-16
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Papatheodorou P, Kindig S, Badilla-Lobo A, Fischer S, Durgun E, Thuraisingam T, Witte A, Song S, Aktories K, Chaves-Olarte E, Rodríguez C, Barth H (2021) The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB. Front Microbiol, 12, 784856, 1-10
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Probst S, Sagar, Tosic J, Schwan C, Grün D, Arnold SJ (2021) Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Development, 48, dev193789, 1-15
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Safaralizade M, Fuderer R, Grosse R, Zhao B (2021) Measuring nuclear calcium and actin assembly in living cells. J Biochem, 169, 287-94
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Szczęśniak P, Henke T, Fröhlich S, Plessmann U, Urlaub H, Leng L, Bucala R, Grosse R, Meinhardt A, Klug J (2021) Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independent of its receptor CD74/CD44. J Cell Sci, 134, jcs217356, 1-12
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Trefzer R, Elpeleg O, Gabrusskaya T, Stepensky P, Mor-Shaked H, Grosse R, Brandt DT (2021) Characterization of a L136P mutation in Formin-like 2 (FMNL2) from a patient with chronic inflammatory bowel disease. PLoS One, 16, e0252428, 1-17
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Ulferts S, Prajapati B, Grosse R, Vartiainen MK (2021) Emerging Properties and Functions of Actin and Actin Filaments Inside the Nucleus. Cold Spring Harb Perspect Biol, 13, 1-16
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Vannini E, Mori E, Tantillo E, Schmidt G, Caleo M, Costa M (2021) CTX-CNF1 Recombinant Protein Selectively Targets Glioma Cells In Vivo. Toxins (Basel), 13, 194, 1-11
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Weigang S, Fuchs J, Zimmer G, Schnepf D, Kern L, Beer J, Luxenburger H, Ankerhold J, Falcone V, Kemming J, Hofmann M, Thimme R, Neumann-Haefelin C, Ulferts S, Grosse R, Hornuss D, Tanriver Y, Rieg S, Wagner D, Huzly D, Schwemmle M, Panning M, Kochs G (2021) Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants. Nat Commun, 12, 6405, 1-12
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Zhao B, Grosse R (2021) Optogenetic Control of Myocardin-Related Transcription Factor A Subcellular Localization and Transcriptional Activity Steers Membrane Blebbing and Invasive Cancer Cell Motility. Adv Biol (Weinh), 5, 2000208, 1-10
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2020 2024 2023 2022 2021 2020 2019

Aktories K (2020) Semaphorins or Frizzled -it is the receptor that direct the action of clostridial glucosylating toxins. Signal Transduct Target Ther, 5, 206, 1-2
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Antoni C, Quentin D, Lang AE, Aktories K, Gatsogiannis C, Raunser S (2020) Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. PLoS Pathog, 16, e1008530, 1-19
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Arlt E, Fraticelli M, Tsvilovskyy V, Nadolni W, Breit A, O'Neill TJ, Resenberger S, Wennemuth G, Wahl-Schott C, Biel M, Grimm C, Freichel M, Gudermann T, Klugbauer N, Boekhoff I, Zierler S (2020) TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity. Proc Natl Acad Sci U S A, 117, 18068-78
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Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Hüttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu J, Bouhaddou S, Mathy CJP, Gaulton A, Manners EJ, Félix E, Shi Y, Goff M, Lim JK, McBride T, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, De Wit E, Leach AR, Kortemme T, Shoichet B, Ott M, Saez-Rodriguez J, tenOever BR, Mullins RD, Fischer ER, Kochs G, Grosse R, García-Sastre A, Vignuzzi M, Johnson JR, Shokat KM, Swaney DL, Beltrao P, Krogan NJ (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell, 182, 685-712
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Fischer S, Ückert AK, Landenberger M, Papatheodorou P, Hoffmann-Richter C, Mittler AK, Ziener U, Hägele M, Schwan C, Müller M, Kleger A, Benz R, Popoff MR, Aktories K, Barth H (2020) Human Peptide α-defensin-1 Interferes With Clostridioides Difficile Toxins TcdA, TcdB, and CDT. FASEB J, 34, 6244-61
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Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR 3rd, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH Jr, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D; QCRG Structural Biology Consortium, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL; Zoonomia Consortium, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, García-Sastre A, Rassen JA, Grosse R, Rosenberg OS, Verba KA, Basler CF, Vignuzzi M, Peden AA, Beltrao P, Krogan NJ (2020) Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science, 370, eabe9403, 1-25
Abstract

Korbmacher M, Fischer S, Landenberger M, Papatheodorou P, Aktories K, Barth H (2020) Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT. Front Pharmacol, 11, 1204, 1-10
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Krippner S, Winkelmeier J, Knerr J, Brandt DT, Virant D, Schwan C, Endesfelder U, Grosse R (2020) Postmitotic expansion of cell nuclei requires nuclear actin filament bundling by α-actinin 4. EMBO Rep, 21, e50758, 1-11
Abstract

Lacinova L, Mallmann RT, Jurkovičová-Tarabová B, Klugbauer N (2020) Modulation of voltage-gated CaV2.2 Ca2+ channels by newly identified interaction partners. Channels (Austin), 14, 380-92
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Mallmann RT, Klugbauer N (2020) Genetic Inactivation of Two-Pore Channel 1 Impairs Spatial Learning and Memory. Behav Genet, 50, 401-10
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Okuno T, Li WY, Hatano Y, Takasu A, Sakamoto Y, Yamamoto M, Ikeda Z, Shindo T, Plessner M, Morita K, Matsumoto K, Yamagata K, Grosse R, Miyamoto K (2020) Zygotic Nuclear F-Actin Safeguards Embryonic Development. Cell Rep, 31, 107824, 1-23
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Ost GS, Wirth C, Bogdanović X, Kao WC, Schorch B, Aktories PJK, Papatheodorou P, Schwan C, Schlosser A, Jank T, Hunte C, Aktories K (2020) Inverse Control of Rab Proteins by Yersinia ADP-ribosyltransferase and Glycosyltransferase Related to Clostridial Glucosylating Toxins. Sci Adv, 6, eaaz2094, 1-12
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Richter L, Oberländer V, Schmidt G (2020) RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A. Sci Rep, 10, 12532, 1-11
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Schiavon, C. R., Zhang, T., Zhao, B., Moore, A. S., Wales, P., Andrade, L. R., Wu, M., Sung, T. C., Dayn, Y., Feng, J. W., Quintero, O. A., Shadel, G. S., Grosse, R., & Manor, U (2020) Actin chromobody imaging reveals sub-organellar actin dynamics. Nature methods, 17, 917–21
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Schwan C, Grosse R (2020) A tight grip on differentiation: Nuclear constriction by microtubules regulates hematopoietic stem cells. EMBO J, e107086, 1-3
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Taskinen ME, Närvä E, Conway JRW, Hinojosa LS, Lilla S, Mai A, De Franceschi N, Elo LL, Grosse R, Zanivan S, Norman JC, Ivaska J (2020) MASTL Promotes Cell Contractility and Motility Through Kinase-Independent Signaling. J Cell Biol, 219, e201906204, 1-23
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Yamazaki S, Gerhold C, Yamamoto K, Ueno Y, Grosse R, Miyamoto K, Harata M (2020) The Actin-Family Protein Arp4 Is a Novel Suppressor for the Formation and Functions of Nuclear F-Actin. Cells, 9, 758, 1-14
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Abdellatif MEA, Hipp L, Plessner M, Walther P, Knöll B (2019) Indirect visualization of endogenous nuclear actin by correlative light and electron microscopy (CLEM) using an actin-directed chromobody. Histochem Cell Biol, 152, 133-43
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Aktories K, Gierschik P, Heringdorf DMZ, Schmidt M, Schultz G, Wieland T (2019) cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology-tribute to Karl H. Jakobs. Naunyn Schmiedebergs Arch Pharmacol, 392, 887-911
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Almonacid M, Al Jord A, El-Hayek S, Othmani A, Coulpier F, Lemoine S, Miyamoto K, Grosse R, Klein C, Piolot T, Mailly P, Voituriez R, Genovesio A, Verlhac MH (2019) Active Fluctuations of the Nuclear Envelope Shape the Transcriptional Dynamics in Oocytes. Dev Cell, 51, 145-57
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Bogdanović X, Schneider S, Levanova N, Wirth C, Trillhaase C, Steinemann M, Hunte C, Aktories K, Jank T (2019) A cysteine protease-like domain enhances the cytotoxic effects of the Photorhabdus asymbiotica toxin PaTox. J Biol Chem, 294, 1035-44
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Brander S, Jank T, Hugel T (2019) AFM Imaging Suggests Receptor-Free Penetration of Lipid Bilayers by Toxins. Langmuir, 35, 365-71
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Caridi CP, Plessner M, Grosse R, Chiolo I (2019) Nuclear actin filaments in DNA repair dynamics. Nat Cell Biol, 21, 1068-77
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Chleilat E, Mallmann R, Spanagel R, Klugbauer N, Krieglstein K, Roussa E (2019) Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons. Front Cell Neurosci, 13, 427, 1-19
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Ebner JK, König GM, Kostenis E, Siegert P, Aktories K, Orth JH (2019) Activation of Gq signaling by Pasteurella multocida toxin inhibits the osteoblastogenic-like actions of Activin A in C2C12 myoblasts, a cell model of fibrodysplasia ossificans progressiva. Bone, 127, 592-601
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Levanova N, Mattheis C, Carson D, To KN, Jank T, Frankel G, Aktories K, Schroeder GN (2019) The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase. J Biol Chem, 294, 2862-79
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Levanova N, Steinemann M, Böhmer KE, Schneider S, Belyi Y, Schlosser A, Aktories K, Jank T (2019) Characterization of the glucosyltransferase activity of Legionella pneumophila effector SetA. Naunyn Schmiedebergs Arch Pharmacol, 392, 69-79
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López-Ureña D, Orozco-Aguilar J, Chaves-Madrigal Y, Ramírez-Mata A, Villalobos-Jimenez A, Ost S, Quesada-Gómez C, Rodríguez C, Papatheodorou P, Chaves-Olarte E (2019) Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors. Toxins (Basel). 11, 384, 1-15
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Mallmann RT, Moravcikova L, Ondacova K, Lacinova L, Klugbauer N (2019) Grina/TMBIM3 modulates voltage-gated Cav2.2 Ca2+ channels in a G-protein-like manner. Cell Calcium, 80, 71-8
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Mallmann R, Ondacova K, Moravcikova L, Jurkovicova-Tarabova B, Pavlovicova M, Moravcik R, Lichvarova L, Kominkova V, Klugbauer N, Lacinova L (2019) Four novel interaction partners demonstrate diverse modulatory effects on voltage-gated CaV2.2 Ca2+ channels. Pflugers Arch, 471, 861-74
Abstract

Müller CS, Bildl W, Klugbauer N, Haupt A, Fakler B, Schulte U (2019) High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis. J Vis Exp, 152, e60096, 1-10
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Ng Ang A PN, Ebner JK, Plessner M, Aktories K, Schmidt G (2019) Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine. Life Sci Alliance, 2, e20190048, 1-12
Abstract

Ost GS, Ng'ang'a PN, Lang A, Aktories K (2019) Photorhabdus luminescens Tc toxin is inhibited by the protease inhibitor MG132 and activated by protease cleavage resulting in increased binding to target cells. Cell Microbiol, 21, e12978, 1-12
Abstract

Papatheodorou P, Song S, López-Ureña D, Witte A, Marques F, Ost GS, Schorch B, Chaves-Olarte E, Aktories K (2019) Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway. FASEB J, 33, 4883-92
Abstract

Plessner M, Grosse R (2019) Dynamizing nuclear actin filaments. Curr Opin Cell Biol, 56, 1-6
Abstract

Plessner M, Knerr J, Grosse R (2019) Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression. iScience, 15, 274-81
Abstract

Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R (2019) Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment. Mol Oncol, 13, 185-201
Abstract

Schnell L, Felix I, Müller B, Sadi M, von Bank F, Papatheodorou P, Popoff MR, Aktories K, Waltenberger E, Benz R, Weichbrodt C, Fauler M, Frick M, Barth H (2019) Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication. FASEB J, 33, 5755-71
Abstract

Stroukov W, Rösch A, Schwan C, Jeney A, Römer W, Thuenauer R (2019) Synchronizing Protein Traffic to the Primary Cilium. Front Genet, 10, 163, 1-10
Abstract

Tsopoulidis N, Kaw S, Laketa V, Kutscheidt S, Baarlink C, Stolp B, Grosse R, Fackler OT (2019) T cell receptor-triggered nuclear actin network formation drives CD4+ T cell effector functions. Sci Immunol, 4, eaav1987, 1-11
Abstract

Wang Y, Sherrard A, Zhao B, Melak M, Trautwein J, Kleinschnitz EM, Tsopoulidis N, Fackler OT, Schwan C, Grosse R (2019) GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics. Nat Commun, 10, 5271, 1-9
Abstract

21 May 2024